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Z Gastroenterol 2025; 63(02): e82-e158
DOI: 10.1055/a-2460-6347
DOI: 10.1055/a-2460-6347
Leitlinie
S3-Leitlinie Diagnostik und Therapie biliärer Karzinome – Langversion
Version 5.1 – August 2024 – AWMF-Registernummer: 032-053OL
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Inhalt |
Seite |
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Wesentliche Neuerungen |
e84 |
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1 |
Informationen zu dieser Leitlinie |
e85 |
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1.1 |
Herausgeber |
e85 |
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1.2 |
Federführende Fachgesellschaft(en) |
e85 |
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1.3 |
Finanzierung der Leitlinie |
e85 |
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1.4 |
Kontakt |
e85 |
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1.5 |
Zitierweise |
e85 |
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1.6 |
Besonderer Hinweis |
e85 |
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1.7 |
Ziele des Leitlinienprogramms Onkologie |
e85 |
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1.8 |
Weitere Dokumente zu dieser Leitlinie |
e86 |
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1.9 |
Zusammensetzung der Leitliniengruppe |
e86 |
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1.9.1 |
Koordination |
e86 |
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1.9.2 |
Beteiligte Fachgesellschaften und Organisationen |
e86 |
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1.9.3 |
Arbeitsgruppen |
e88 |
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1.9.4 |
Patientenbeteiligung |
e88 |
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1.9.5 |
Methodische Begleitung |
e88 |
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1.10 |
Abkürzungsverzeichnis |
e88 |
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2 |
Einführung |
e91 |
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2.1 |
Geltungsbereich und Zweck |
e91 |
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2.1.1 |
Zielsetzung und Fragestellung |
e91 |
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2.1.2 |
Adressaten |
e91 |
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2.1.3 |
Gültigkeitsdauer und Aktualisierungsverfahren |
e92 |
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2.2 |
Grundlagen der Methodik |
e92 |
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2.2.1 |
Schema der Evidenzgraduierung |
e92 |
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2.2.2 |
Schema der Empfehlungsgraduierung |
e92 |
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2.2.3 |
Statements |
e92 |
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2.2.4 |
Expertenkonsens (EK) |
e92 |
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2.2.5 |
Unabhängigkeit und Darlegung möglicher Interessenkonflikte |
e94 |
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3 |
Diagnostik und Therapie der biliären Karzinome |
e95 |
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3.1 |
Risikofaktoren, Prävention und Früherkennung |
e95 |
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3.1.1 |
Risikofaktoren |
e95 |
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3.1.2 |
Prophylaktische und therapeutische Maßnahmen zur Risikoreduktion der Entstehung von biliären Karzinomen |
e96 |
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3.1.3 |
Früherkennung |
e97 |
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3.2 |
Histopathologische und molekulare Diagnostik |
e97 |
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3.2.1 |
Typisierung und Staging von biliären Karzinomen |
e97 |
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3.2.2 |
Zytologische und histopathologische Untersuchungen zur Diagnostik eines CCA, eines Gallenblasenkarzinoms |
e99 |
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3.2.3 |
Molekulare Diagnostik |
e100 |
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3.3 |
Bildgebende und endoskopische Diagnostik |
e101 |
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3.3.1 |
Bildgebende und/oder endoskopische Untersuchungen zum Staging und zur Diagnosestellung eines biliären Karzinoms |
e101 |
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3.3.2 |
Untersuchungsmethoden zur Darstellung der maximalen Ausbreitung des Tumors |
e102 |
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3.3.3 |
Diagnostikalgorithmus |
e103 |
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3.3.4 |
Endoskopische Diagnostik |
e104 |
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3.4 |
Operative und interventionelle Therapieverfahren |
e105 |
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3.4.1 |
Resektion |
e105 |
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3.4.2 |
Lebertransplantation |
e107 |
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3.4.3 |
Interventionelle Therapieverfahren |
e108 |
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3.4.4 |
Endoskopische Therapieverfahren |
e109 |
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3.4.5 |
Stereotaxie |
e111 |
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3.4.6 |
Nachsorge |
e112 |
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3.5 |
Systemtherapie |
e112 |
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3.5.1 |
Adjuvante Therapie |
e112 |
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3.5.2 |
Neoadjuvante Therapie primär resektabler Tumoren |
e113 |
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3.5.3 |
Systemtherapie lokal fortgeschrittener Tumoren |
e113 |
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3.5.4 |
Palliative Systemtherapie |
e113 |
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3.5.5 |
Therapie nach Versagen der Erstlinientherapie |
e114 |
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3.5.6 |
Verlaufskontrollen unter Systemtherapie |
e117 |
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4 |
Supportivtherapie des Hepatozellulären Karzinoms und der biliären Karzinome |
e117 |
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4.1 |
Ernährung |
e117 |
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4.2 |
Palliativmedizinische Behandlung beim HCC/CCA |
e117 |
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4.3 |
Integration von Palliativversorgung |
e118 |
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4.3.1 |
Zeitpunkt der Integration von Palliativversorgung beim HCC/CCA |
e118 |
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4.4 |
Palliative Symptomkontrolle bei Patienten mit HCC/CCA |
e118 |
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4.5 |
Rehabilitation, Sport- und Bewegungstherapie |
e119 |
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4.6 |
Psychoonkologie |
e120 |
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4.6.1 |
Patientenzentrierte Kommunikation, Information und Aufklärung |
e120 |
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5 |
Forschungsfragen |
e121 |
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6 |
Qualitätsindikatoren |
e121 |
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7 |
Anhang |
e125 |
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7.1 |
Literaturübersichten |
e125 |
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7.1.1 |
Kapitel 4.4. Operative und Interventionelle Therapie der biliären Karzinome |
e125 |
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7.2 |
Übersicht der Änderungen von Version 4 zur Version 5 |
e127 |
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8 |
Tabellenverzeichnis |
e128 |
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9 |
Abbildungsverzeichnis |
e128 |
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10 |
Literaturverzeichnis |
e128 |
Publication History
Article published online:
07 February 2025
© 2025. Thieme. All rights reserved.
Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
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