CC BY 4.0 · Endoscopy
DOI: 10.1055/a-2371-3693
Original article

Polyp size measurement during colonoscopy using a virtual scale: variability and systematic differences

Querijn N.E. van Bokhorst
1   Department of Gastroenterology and Hepatology, Amsterdam UMC Location VUmc, Amsterdam, Netherlands (Ringgold ID: RIN1209)
2   Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, Netherlands (Ringgold ID: RIN571165)
3   Gastroenterology and Hepatology, Cancer Center Amsterdam, Amsterdam, Netherlands
,
1   Department of Gastroenterology and Hepatology, Amsterdam UMC Location VUmc, Amsterdam, Netherlands (Ringgold ID: RIN1209)
2   Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, Netherlands (Ringgold ID: RIN571165)
3   Gastroenterology and Hepatology, Cancer Center Amsterdam, Amsterdam, Netherlands
,
Yark Hazewinkel
4   Department of Gastroenterology and Hepatology, Ter Gooi Medical Center, Hilversum, Netherlands
,
Manon van der Vlugt
1   Department of Gastroenterology and Hepatology, Amsterdam UMC Location VUmc, Amsterdam, Netherlands (Ringgold ID: RIN1209)
2   Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, Netherlands (Ringgold ID: RIN571165)
5   Gastroenterology and Hepatology, Cancer Center Amsterdam, Amsterdam, Netherlands
6   Department of Gastroenterology, Bergman Clinics, Amsterdam, Netherlands
,
Hanneke Beaumont
1   Department of Gastroenterology and Hepatology, Amsterdam UMC Location VUmc, Amsterdam, Netherlands (Ringgold ID: RIN1209)
2   Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, Netherlands (Ringgold ID: RIN571165)
3   Gastroenterology and Hepatology, Cancer Center Amsterdam, Amsterdam, Netherlands
6   Department of Gastroenterology, Bergman Clinics, Amsterdam, Netherlands
,
Joep Grootjans
1   Department of Gastroenterology and Hepatology, Amsterdam UMC Location VUmc, Amsterdam, Netherlands (Ringgold ID: RIN1209)
3   Gastroenterology and Hepatology, Cancer Center Amsterdam, Amsterdam, Netherlands
6   Department of Gastroenterology, Bergman Clinics, Amsterdam, Netherlands
7   Gastroenterology and Hepatology, Oncode Institute, Amsterdam, Netherlands
,
Arjan van Tilburg
8   Department of Pathology, Reinier de Graaf Gasthuis, Delft, Netherlands (Ringgold ID: RIN84744)
,
Marlou P.M. Adriaanse
1   Department of Gastroenterology and Hepatology, Amsterdam UMC Location VUmc, Amsterdam, Netherlands (Ringgold ID: RIN1209)
,
Barbara A.J. Bastiaansen
1   Department of Gastroenterology and Hepatology, Amsterdam UMC Location VUmc, Amsterdam, Netherlands (Ringgold ID: RIN1209)
2   Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, Netherlands (Ringgold ID: RIN571165)
3   Gastroenterology and Hepatology, Cancer Center Amsterdam, Amsterdam, Netherlands
,
Yvette H. van Beurden
1   Department of Gastroenterology and Hepatology, Amsterdam UMC Location VUmc, Amsterdam, Netherlands (Ringgold ID: RIN1209)
,
Maxime E.S. Bronzwaer
1   Department of Gastroenterology and Hepatology, Amsterdam UMC Location VUmc, Amsterdam, Netherlands (Ringgold ID: RIN1209)
,
Brecht W.E. Hens
1   Department of Gastroenterology and Hepatology, Amsterdam UMC Location VUmc, Amsterdam, Netherlands (Ringgold ID: RIN1209)
,
Lowiek M. Hubers
1   Department of Gastroenterology and Hepatology, Amsterdam UMC Location VUmc, Amsterdam, Netherlands (Ringgold ID: RIN1209)
,
Gem M. Kramer
1   Department of Gastroenterology and Hepatology, Amsterdam UMC Location VUmc, Amsterdam, Netherlands (Ringgold ID: RIN1209)
,
Selma J. Lekkerkerker
9   Department of Gastroenterology and Hepatology, Amsterdam UMC Locatie VUmc, Amsterdam, Netherlands (Ringgold ID: RIN1209)
,
Berrie Meijer
10   Department of Gastroenterology and Hepatology, Dijklander Ziekenhuis, Hoorn and Purmerend, Netherlands (Ringgold ID: RIN3956)
,
Fraukje A. Ponds
1   Department of Gastroenterology and Hepatology, Amsterdam UMC Location VUmc, Amsterdam, Netherlands (Ringgold ID: RIN1209)
,
Dewkoemar Ramsoekh
1   Department of Gastroenterology and Hepatology, Amsterdam UMC Location VUmc, Amsterdam, Netherlands (Ringgold ID: RIN1209)
2   Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, Netherlands (Ringgold ID: RIN571165)
3   Gastroenterology and Hepatology, Cancer Center Amsterdam, Amsterdam, Netherlands
6   Department of Gastroenterology, Bergman Clinics, Amsterdam, Netherlands
,
Paul Fockens
11   Gastroenterology and Hepatology, Amsterdam UMC Location VUmc, Amsterdam, Netherlands (Ringgold ID: RIN1209)
2   Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, Netherlands (Ringgold ID: RIN571165)
3   Gastroenterology and Hepatology, Cancer Center Amsterdam, Amsterdam, Netherlands
,
Patrick M.M. Bossuyt
12   Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam UMC Location AMC, Amsterdam, Netherlands (Ringgold ID: RIN26066)
,
1   Department of Gastroenterology and Hepatology, Amsterdam UMC Location VUmc, Amsterdam, Netherlands (Ringgold ID: RIN1209)
2   Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, Netherlands (Ringgold ID: RIN571165)
3   Gastroenterology and Hepatology, Cancer Center Amsterdam, Amsterdam, Netherlands
6   Department of Gastroenterology, Bergman Clinics, Amsterdam, Netherlands
› Author Affiliations
Supported by: Fujifilm Corporation Unrestricted research grant

Clinical Trial: Registration number (trial ID): NCT05499546, Trial registry: ClinicalTrials.gov (http://www.clinicaltrials.gov/), Type of Study: Video-based study

Background Accurate polyp size measurement is important for polyp risk stratification and decision-making regarding polypectomy and surveillance. Recently, a virtual scale (VS) function has been developed that allows polyp size measurement through projection of an adaptive VS onto colorectal polyps during real-time endoscopy. We aimed to evaluate the VS in terms of variability and systematic differences. Methods We conducted a video-based study with 120 colorectal polyps, measured by eight dedicated colorectal gastroenterologists (experts) and nine gastroenterology residents following endoscopy training (trainees). Three endoscopic measurement methods were compared: (1) visual, (2) snare and (3) VS measurement. We evaluated the method-specific variance (as measure of variability) in polyp size measurements and systematic differences between these methods. Results Variance in polyp size measurements was significantly lower for VS measurements compared to visual and snare measurements for both experts (0.52 vs. 1.59 and 1.96, p<0.001) and trainees (0.59 vs. 2.21 and 2.53, p<0.001). VS measurement resulted in a higher percentage of polyps assigned to the same size category by all endoscopists compared to visual and snare measurements (experts: 69% vs. 55% and 59%; trainees: 67% vs. 51% and 47%) and reduced the maximum difference between individual endoscopists regarding the percentage of polyps assigned to the <u>></u>10 mm size category (experts: 1.7% vs. 10.0% and 5.0%; trainees: 2.5% vs. 6.7% and 11.7%). Systematic differences between methods were <0.5 mm. <b>Conclusions</b> Use of the VS leads to lower polyp size measurement variability and more uniform polyp sizing by individual endoscopists compared to visual and snare measurements.



Publication History

Received: 02 April 2024

Accepted after revision: 18 July 2024

Accepted Manuscript online:
23 July 2024

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