RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000084.xml
Synthesis
DOI: 10.1055/a-2311-3930
DOI: 10.1055/a-2311-3930
paper
Pd-catalyzed regioselective tandem C-S/C-N bond formation for modular synthesis of pyrimidine-fused benzothiazoles from o-dihaloarenes and 3,4-dihydropyrimidin-2-thiones
Gefördert durch: the Natural Science Foundation of Heilongjiang Province LH2022B003,ZD2021C001Gefördert durch: the National Natural Science Foundation of China 32370413
Gefördert durch: the Fundamental Research Funds for the Central Universities 2572023CT12
A Pd-catalyzed annulation reaction for the synthesis of 4H-pyrimido[2,1-b]benzothiazole derivatives via regioselective tandem C-S/C-N bond formation was developed. With PdCl2(PPh3)2 as the precatalyst, Davephos as the ligand, and K2CO3 as the base, various 3,4-dihydropyrimidin-2-thiones with o-dihaloarenes proceeded smoothly, and the desired products were obtained in moderate to good yields
Publikationsverlauf
Eingereicht: 21. Februar 2024
Angenommen nach Revision: 22. April 2024
Accepted Manuscript online:
22. April 2024
© . Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany