Gel immersion endoscopic mucosal resection for early gastric neoplasms: a multicenter case series study

Abstract

Several cases have been reported that suggest the efficacy of gel immersion endoscopic mucosal resection (GI-EMR) for gastric neoplasms. However, no study has evaluated treatment outcomes of GI-EMR for gastric neoplasms. This study aimed to investigate the efficacy and safety of GI-EMR for early gastric neoplasms. Nine patients (17 lesions) undergoing gastric GI-EMR were included, with a median lesion size of 10 mm (interquartile range [IQR] 5–13 mm). All lesions were protruding or flat elevated. The median procedure time was 3 minutes (IQR 2–5) and en bloc resection was achieved in all cases. Among 15 neoplastic lesions, the R0 resection rate was 86.7% (13/15 lesions). Adverse events included immediate bleeding requiring hemostasis in two cases, which was controlled endoscopically. No delayed bleeding or perforation occurred. In conclusion, GI-EMR may be a safe and effective treatment for early, small gastric neoplasms. However, due to the small sample in the present study, further investigation is required regarding the indication for this technique.

Keywords

Endoscopic resection (ESD, EMRc, ...) - Endoscopy Upper GI Tract - Precancerous conditions & cancerous lesions (displasia and cancer) stomach

Publication History

Received: 25 November 2023

Accepted after revision: 15 February 2024

Accepted Manuscript online:
19 February 2024

Article published online:
18 March 2024

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