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DOI: 10.1055/a-2258-0531
Endoskopische Diagnostik und Therapie von malignen epithelialen Läsionen und ihren Vorläufern im Ösophagus
Endoscopic Diagnosis and Treatment of Early Mucosal Neoplasms in the OesophagusZusammenfassung
Die Endoskopie ist der Goldstandard für die Diagnose von bösartigen Tumoren des Ösophagus und ihren Vorläuferläsionen. Darüber hinaus ist die endoskopische Behandlung dieser Vorläuferläsionen und des frühen Ösophaguskarzinoms gut untersucht und fest etabliert. Dazu gehören dysplastische Läsionen im Zusammenhang mit dem Barrett-Ösophagus und frühe Adenokarzinome sowie frühe Plattenepithelkarzinome des Ösophagus. Die Rolle der Endoskopie bei der Diagnose und Behandlung dieser Läsionen wird zusammenfassend dargestellt.
Abstract
Endoscopy is the gold standard for diagnosis of oesophageal cancer and its precursor lesions. Besides this, endoscopy treatment of these precursor lesions and early oesophageal cancer has been well evaluated and established. This includes dysplastic lesions associated with Barrett’s oesophagus and early adenocarcinoma, as well as early squamous cell cancer of the oesophagus. The role of endoscopy for diagnosis and treatment of these lesions is summarised.
Schlüsselwörter
Adenom - Endoskopie - endoskopische Chirurgie - endoskopische Intervention - GastrointestinaltumorPublication History
Received: 10 January 2024
Accepted: 24 January 2024
Article published online:
06 March 2024
© 2024. Thieme. All rights reserved.
Georg Thieme Verlag KG
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Literatur
- 1 Robert Koch-Institut, Gesellschaft der epidemiologischen Krebsregister in Deutschland e. V.. Krebs in Deutschland für 2019/2020. 14. Ausgabe. Berlin 2023 Accessed February 13, 2024 at: https://www.krebsdaten.de/Krebs/DE/Content/Publikationen/Krebs_in_Deutschland/krebs_in_deutschland_2023.pdf?__blob=publicationFile
- 2 Porschen R, Fischbach W, Gockel I. et al. S3-Leitlinie Diagnostik und Therapie der Plattenepithelkarzinome und Adenokarzinome des Ösophagus. Z Gastroenterol 2023; 61: e209-e307 DOI: 10.1055/a-1771-6953.
- 3 Sharma P, Bergman JJ, Goda K. et al. Development and Validation of a Classification System to Identify High-Grade Dysplasia and Esophageal Adenocarcinoma in Barrett’s Esophagus Using Narrow-Band Imaging. Gastroenterology 2016; 150: 591-598 DOI: 10.1053/j.gastro.2015.11.037. (PMID: 26627609)
- 4 Kandiah K, Chedgy FJQ, Subramaniam S. et al. International development and validation of a classification system for the identification of Barrett’s neoplasia using acetic acid chromoendoscopy: the Portsmouth acetic acid classification (PREDICT). Gut 2018; 67: 2085-2091 DOI: 10.1136/gutjnl-2017-314512. (PMID: 28970288)
- 5 Nihei K, Minashi K, Yano T. et al. Final Analysis of Diagnostic Endoscopic Resection Followed by Selective Chemoradiotherapy for Stage I Esophageal Cancer: JCOG0508. Gastroenterology 2023; 164: 296-299.e2 DOI: 10.1053/j.gastro.2022.10.002.
- 6 Weusten B, Bisschops R, Dinis-Ribeiro M. et al. Diagnosis and management of Barrett esophagus: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy 2023; 55: 1124-1146 DOI: 10.1055/a-2176-2440. (PMID: 37813356)
- 7 Pouw RE, Klaver E, Phoa KN. et al. Radiofrequency ablation for low-grade dysplasia in Barrett’s esophagus: long-term outcome of a randomized trial. Gastrointest Endosc 2020; 92: 569-574 DOI: 10.1016/j.gie.2020.03.3756. (PMID: 32217112)
- 8 Krishnamoorthi R. Endoscopic therapy or surveillance for Barrett’s esophagus with low-grade dysplasia: time to involve patients in shared decision making. Gastrointest Endosc 2020; 92: 575-577 DOI: 10.1016/j.gie.2020.05.007. (PMID: 32838907)
- 9 Nieuwenhuis EA, van Munster SN, Meijer SL. et al. Analysis of metastases rates during follow-up after endoscopic resection of early “high-risk” esophageal adenocarcinoma. Gastrointest Endosc 2022; 96: 237-247.e3 DOI: 10.1016/j.gie.2022.03.005.
- 10 Ishihara R, Arima M, Iizuka T. et al. Endoscopic submucosal dissection/endoscopic mucosal resection guidelines for esophageal cancer. Dig Endosc 2020; 32: 452-493 DOI: 10.1111/den.13654. (PMID: 32072683)
- 11 Yamaguchi N, Isomoto H, Nakayama T. et al. Usefulness of oral prednisolone in the treatment of esophageal stricture after endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma. Gastrointest Endosc 2011; 73: 1115-1121 DOI: 10.1016/j.gie.2011.02.005. (PMID: 21492854)
- 12 Bartel MJ, Mousa OY, Brahmbhatt B. et al. Impact of topical budesonide on prevention of esophageal stricture after mucosal resection. Gastrointest Endosc 2021; 93: 1276-1282 DOI: 10.1016/j.gie.2020.11.026. (PMID: 33309653)
- 13 Ladd AM, Park K, Bilal M. et al. Prophylactic stenting to decrease the incidence of esophageal strictures after extensive endoscopic submucosal dissection: the first U.S. experience. Gastrointest Endosc 2023; 98: 1000-1003 DOI: 10.1016/j.gie.2023.07.033. (PMID: 37500020)
- 14 Tavares G, Tustumi F, Tristao LS. et al. Endoscopic vacuum therapy for anastomotic leak in esophagectomy and total gastrectomy: a systematic review and meta-analysis. Dis Esophagus 2021; 34: doaa132 DOI: 10.1093/dote/doaa132. (PMID: 33479749)