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CC BY-NC-ND 4.0 · Endosc Int Open 2024; 12(03): E332-E338
DOI: 10.1055/a-2215-3284
Original article

Characteristic endoscopic findings in early-stage autoimmune gastritis

Tohru Kotera
1   Department of Medical Examination, Uji Tokushukai Medical Center, Uji, Japan (Ringgold ID: RIN36878)
,
Maki Ayaki
2   Division of Endoscopy and Ultrasonography, Department of Clinical Pathology and Laboratory Medicine, Kawasaki Medical School, Okayama, Japan (Ringgold ID: RIN12864)
,
Naoki Sumi
3   Department of Health Care Medicine, Kawasaki Medical School, Kurashiki, Japan (Ringgold ID: RIN12864)
,
Rika Aoki
4   Department of Health Screening, Tokushima Health Screening Center, Tokushima, Japan
,
Katsuhiro Mabe
5   Department of Gastroenterology, Junpukai Health Maintenance Center-Kurashiki, Kurashiki, Japan
,
Kazuhiko Inoue
6   Health Care Medicine, Junpukai Health Maintenance Center, Okayama, Japan
,
Noriaki Manabe
2   Division of Endoscopy and Ultrasonography, Department of Clinical Pathology and Laboratory Medicine, Kawasaki Medical School, Okayama, Japan (Ringgold ID: RIN12864)
,
Tomoari Kamada
7   Department of Health Care Medicine, Kawasaki Medical School General Medical Center, Okayama, Japan
,
Ryoji Kushima
8   Department of Pathology, Shiga University of Medical Science, Otsu, Japan (Ringgold ID: RIN13051)
,
Ken Haruma
9   Department of Internal Medicine 2, Kawasaki Medical School General Medical Center, Okayama, Japan
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Abstract

Background and study aims Until recently, autoimmune gastritis (AIG) was usually diagnosed at late stages based on typical endoscopic findings, including corpus-dominant advanced atrophy. Early-stage AIG prior to complete gastric atrophy had rarely been diagnosed due to a lack of knowledge about its endoscopic characteristics. The present study sought to identify the endoscopic characteristics of early-stage AIG, enabling its early diagnosis.

Patients and methods The clinical and endoscopic findings of 12 patients diagnosed with early-stage AIG between 2016 and 2021 were retrospectively evaluated. Patients were included if they were: (1) positive for serum anti-parietal cell antibody; (2) diagnosed with histological early-stage AIG; and (3) endoscopically positive for folds on the greater curvature of the gastric corpus.

Results Two characteristic endoscopic findings of early-stage AIG were identified: longitudinal alignment of pseudopolyps (i.e., a bamboo joint-like appearance) and swelling of gastric areas with erythema (i.e., a salmon roe-like appearance).

Conclusions Endoscopic findings characteristic of early-stage AIG include a bamboo joint-like appearance and a salmon roe-like appearance. Studies in large numbers of patients with long-term follow-up are needed to confirm these findings.

Keywords

autoimmune gastritis - early stage - endoscopy


Publication History

Received: 12 May 2023

Accepted after revision: 16 November 2023

Accepted Manuscript online:
21 November 2023

Article published online:
07 March 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

Comment to this article:

Endoscopy International Open – recently publishedEndoscopy 2024; 56(05): 394-394
DOI: 10.1055/a-2252-3068

 

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