CC BY-NC-ND 4.0 · AJP Rep 2024; 14(01): e74-e79
DOI: 10.1055/a-2164-8100
Case Report

Uterine Leiomyomata as a Cause of Abdominal Compartment Syndrome in the Postpartum Period

Mason Hui
1   Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas
,
Baha Sibai
1   Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas
,
Alvaro Montealegre
1   Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas
,
Mateo G. Leon
1   Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas
› Author Affiliations
Funding None.

Abstract

Uterine leiomyomas are common benign smooth muscle tumors that often occur during the reproductive years. Although many cases may not result in significant complications, negative pregnancy outcomes have been associated with the size and location of the fibroids. Degeneration of fibroids can occur as early as the late first trimester when they undergo significant volumetric growth, contributing to pain during pregnancy. While myomectomy is typically avoided during pregnancy, conservative management with anti-inflammatory medications may be effective. Surgical removal or preterm delivery may be necessary if symptoms persist. Abdominal compartment syndrome (ACS) is a rare condition characterized by sustained elevated intra-abdominal pressure leading to organ failure. Although ACS resulting from large-volume leiomyomas in the postpartum period has not been previously described, we present a case of a 25-year-old patient with massive uterine fibroids who required indicated preterm delivery via primary cesarean section at 25 weeks gestation. Her postpartum course was complicated by ACS, requiring emergent surgical decompression. When a large fibroid burden is present during pregnancy or in the postpartum period, ACS should be considered in the differential diagnosis. Early diagnosis and timely surgical decompression are necessary to prevent organ dysfunction and worsening maternal outcomes.

Informed Consent

The authors confirm that written permission from the patient on whom the report is based has been obtained.




Publication History

Received: 29 May 2023

Accepted: 17 August 2023

Accepted Manuscript online:
01 September 2023

Article published online:
18 February 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA

 
  • References

  • 1 Klatsky PC, Tran ND, Caughey AB, Fujimoto VY. Fibroids and reproductive outcomes: a systematic literature review from conception to delivery. Am J Obstet Gynecol 2008; 198 (04) 357-366
  • 2 Egbe TO, Badjang TG, Tchounzou R, Egbe EN, Ngowe MN. Uterine fibroids in pregnancy: prevalence, clinical presentation, associated factors and outcomes at the Limbe and Buea Regional Hospitals, Cameroon: a cross-sectional study. BMC Res Notes 2018; 11 (01) 889
  • 3 Katz VL, Dotters DJ, Droegemeuller W. Complications of uterine leiomyomas in pregnancy. Obstet Gynecol 1989; 73 (04) 593-596
  • 4 Febo G, Tessarolo M, Leo L, Arduino S, Wierdis T, Lanza L. Surgical management of leiomyomata in pregnancy. Clin Exp Obstet Gynecol 1997; 24 (02) 76-78
  • 5 De Carolis S, Fatigante G, Ferrazzani S. et al. Uterine myomectomy in pregnant women. Fetal Diagn Ther 2001; 16 (02) 116-119
  • 6 Spyropoulou K, Kosmas I, Tsakiridis I. et al. Myomectomy during pregnancy: a systematic review. Eur J Obstet Gynecol Reprod Biol 2020; 254: 15-24
  • 7 Malbrain ML, Chiumello D, Pelosi P. et al. Prevalence of intra-abdominal hypertension in critically ill patients: a multicentre epidemiological study. Intensive Care Med 2004; 30 (05) 822-829
  • 8 Hong JJ, Cohn SM, Perez JM, Dolich MO, Brown M, McKenney MG. Prospective study of the incidence and outcome of intra-abdominal hypertension and the abdominal compartment syndrome. Br J Surg 2002; 89 (05) 591-596
  • 9 Kirkpatrick AW, Brenneman FD, McLean RF, Rapanos T, Boulanger BR. Is clinical examination an accurate indicator of raised intra-abdominal pressure in critically injured patients?. Can J Surg 2000; 43 (03) 207-211
  • 10 Malbrain ML, Cheatham ML, Kirkpatrick A. et al. Results from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome. I. Definitions. Intensive Care Med 2006; 32 (11) 1722-1732 DOI: 10.1007/s00134-006-0349-5. Epub 2006 Sep 12. PMID: 16967294.
  • 11 Khormi GJ, Ageeli RS, Othathi RJ, Bingasem SM, Al Ghadeeb M. Abdominal compartment syndrome due to large ovarian cystadenoma: a case report. Cureus 2022; 14 (11) e31389
  • 12 Sugrue M. Abdominal compartment syndrome. Curr Opin Crit Care 2005; 11 (04) 333-338
  • 13 Dries DJ. Abdominal compartment syndrome: toward less-invasive management. Chest 2011; 140 (06) 1396-1398
  • 14 Cheatham ML. Nonoperative management of intraabdominal hypertension and abdominal compartment syndrome. World J Surg 2009; 33 (06) 1116-1122
  • 15 Hirata M, Hasegawa K, Kasuga Y. et al. A case of abdominal compartment syndrome caused by amniotic fluid embolism treated with ABTHERA™ therapy: World's first report in the obstetric field. Taiwan J Obstet Gynecol 2021; 60 (03) 579-580
  • 16 Lam SJ, Best S, Kumar S. The impact of fibroid characteristics on pregnancy outcome. Am J Obstet Gynecol 2014; 211 (04) 395.e1-395.e5
  • 17 Petrenko AP, Castelo-Branco C, Marshalov DV. et al. Physiology of intra-abdominal volume during pregnancy. J Obstet Gynaecol 2021; 41 (07) 1016-1022
  • 18 Mitro SD, Peddada S, Chen Z. et al. Natural history of fibroids in pregnancy: National Institute of Child Health and Human Development Fetal Growth Studies - Singletons cohort. Fertil Steril 2022; 118 (04) 656-665
  • 19 Chabbert-Buffet N, Esber N, Bouchard P. Fibroid growth and medical options for treatment. Fertil Steril 2014; 102 (03) 630-639
  • 20 Eldar-Geva T, Meagher S, Healy DL, MacLachlan V, Breheny S, Wood C. Effect of intramural, subserosal, and submucosal uterine fibroids on the outcome of assisted reproductive technology treatment. Fertil Steril 1998; 70 (04) 687-691
  • 21 Pérez-Roncero GR, López-Baena MT, Ornat L. et al. Uterine fibroids and preterm birth risk: a systematic review and meta-analysis. J Obstet Gynaecol Res 2020; 46 (09) 1711-1727
  • 22 Lee HJ, Norwitz ER, Shaw J. Contemporary management of fibroids in pregnancy. Rev Obstet Gynecol 2010; 3 (01) 20-27
  • 23 Treissman DA, Bate JT, Randall PT. Epidural use of morphine in managing the pain of carneous degeneration of a uterine leiomyoma during pregnancy. Can Med Assoc J 1982; 126 (05) 505-506
  • 24 Vitale SG, Padula F, Gulino FA. Management of uterine fibroids in pregnancy: recent trends. Curr Opin Obstet Gynecol 2015; 27 (06) 432-437
  • 25 von Gruenigen VE, Coleman RL, King MR, Miller DS. Abdominal compartment syndrome in gynecologic surgery. Obstet Gynecol 1999; 94 (5 Pt 2): 830-832
  • 26 Chao A, Chao A, Yen YS, Huang CH. Abdominal compartment syndrome secondary to ovarian mucinous cystadenoma. Obstet Gynecol 2004; 104 (5 Pt 2): 1180-1182
  • 27 Soltsman S, Russo P, Greenshpun A, Ben-Ami M. Abdominal compartment syndrome after laparoscopic salpingectomy for ectopic pregnancy. J Minim Invasive Gynecol 2008; 15 (04) 508-510
  • 28 Chang MC, Miller PR, D'Agostino Jr R, Meredith JW. Effects of abdominal decompression on cardiopulmonary function and visceral perfusion in patients with intra-abdominal hypertension. J Trauma 1998; 44 (03) 440-445
  • 29 Cheatham ML, Safcsak K. Is the evolving management of intra-abdominal hypertension and abdominal compartment syndrome improving survival?. Crit Care Med 2010; 38 (02) 402-407
  • 30 Schein M, Ivatury R. Intra-abdominal hypertension and the abdominal compartment syndrome. Br J Surg 1998; 85 (08) 1027-1028
  • 31 Staelens AS, Van Cauwelaert S, Tomsin K, Mesens T, Malbrain ML, Gyselaers W. Intra-abdominal pressure measurements in term pregnancy and postpartum: an observational study. PLoS One 2014; 9 (08) e104782
  • 32 Vidal MG, Ruiz Weisser J, Gonzalez F. et al. Incidence and clinical effects of intra-abdominal hypertension in critically ill patients. Crit Care Med 2008; 36 (06) 1823-1831
  • 33 Kaufman C, Pollak J, Mojibian H. What is too big? Uterine artery embolization of a large fibroid causing abdominal compartment syndrome. Semin Intervent Radiol 2014; 31 (02) 207-211