Practical Asymmetric Synthesis of Sulfoximines and Sulfimides from Sulfinamides

Abstract

Chiral sulfoximines and sulfimides are an interesting class of compounds in various areas. However, methodologies for preparing these chiral sulfur compounds in a stereoselective manner have been underdeveloped. Herein, we briefly summarize our recent studies on asymmetric synthesis of sulfoximines and sulfimides from readily available enantioenriched sulfinamides. In these studies, optically pure sulfoximines and sulfimides having various carbon substituents on their sulfur atom could be obtained.

1 Introduction

2 Asymmetric Synthesis of Chiral Sulfoximines

3 Asymmetric Synthesis of Chiral Sulfimides

4 Conclusion

Key words

asymmetric synthesis - chirality - sulfinamides - sulfoximines - sulfimides - sulfinimidate esters

Publication History

Received: 21 June 2023

Accepted after revision: 11 July 2023

Accepted Manuscript online:
11 July 2023

Article published online:
05 September 2023

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