The synthesis of two diastereomeric steroid spiroketals bearing a 2,3-dihydrobenzofuran moiety is described. The structure of the obtained compounds was elucidated by combined 1D and 2D NMR techniques and corroborated by X-ray crystallography studies.
Key words
steroids - benzofuran spiroketals - palladium-catalyzed spiroketalization - NMR - X-ray diffraction