Physikalische Medizin, Rehabilitationsmedizin, Kurortmedizin 2024; 34(02): 72-78
DOI: 10.1055/a-2006-4248
Original Article

Efficacy of Work-Related Support Rehabilitation for Patients with Cancer: A Meta-Analysis of Randomized Controlled Trials

Wirksamkeit der berufsbezogenen unterstützenden Rehabilitation bei Krebspatienten: Eine Metaanalyse von randomisierten kontrollierten Studien
Gang Li
1   Department of Oncology, Tianshui Hospital of Integrated Traditional Chinese and Western Medicine, Gansu Province
,
Bin Wang
2   General Surgery, Tianshui Hospital of Integrated Traditional Chinese and Western Medicine, Gansu Province
,
Yunzhou Hu
2   General Surgery, Tianshui Hospital of Integrated Traditional Chinese and Western Medicine, Gansu Province
,
Xiaolong Wang
2   General Surgery, Tianshui Hospital of Integrated Traditional Chinese and Western Medicine, Gansu Province
› Author Affiliations

Abstract

Introduction The efficacy of work-related support rehabilitation for patients with cancer remains controversial. We conduct a systematic review and meta-analysis to explore the influence of work-related support rehabilitation on the quality of life in patients with cancer.

Methods We have searched Pubmed, Embase, Web of science, Ebsco, and Cochrane library databases through August 2021 for randomized controlled trials (RCTs) assessing the effect of work-related support rehabilitation on the quality of life in patients with cancer. This meta-analysis is performed using the random-effect model.

Results Four RCTs are included in the meta-analysis. Overall, compared with usual care for cancer patients, work-related support is associated with significantly improved quality of life physical score (PCS, standard mean difference [SMD]=0.22; 95% confidence interval [CI]=0.06 to 0.37; P=0.005) and reduced quality of life pain (SMD=−0.16; 95% CI=−0.31 to 0; P=0.04), but showed no obvious impact on quality of life mental score (MCS, SMD=0; 95% CI=−0.28 to 0.28; P=0.98), time of return to work (SMD=−0.78; 95% CI=−2.71 to 1.14; P=0.43), or the scores of work ability (SMD=−0.01; 95% CI=−0.16 to 9.09; P=0.13) and work limitation (SMD=0.12; 95% CI=−0.16 to 0.40; P=0.41).

Conclusions Work-related support rehabilitation may be effective to improve the quality of life of cancer patients.

Zusammenfassung

Hintergrund und Ziel Die Wirksamkeit der berufsbezogenen unterstützenden Rehabilitation für Krebspatienten ist nach wie vor umstritten. Wir erstellten einen systematischen Review mit Metaanalyse, um den Einfluss der berufsbezogenen unterstützenden Rehabilitation auf die Lebensqualität von Krebspatienten zu untersuchen.

Methodik Wir führten eine Suche in den Datenbanken Pubmed, Embase, Web of Science, Ebsco und Cochrane Library nach bis August 2021 erschienenen randomisierten kontrollierten Studien (RCTs) durch, die sich mit der Wirkung der berufsbezogenen unterstützenden Rehabilitation auf die Lebensqualität von Krebspatienten befassen. Die Metaanalyse erfolgte unter Nutzung eines Random Effects-Modells.

Ergebnisse Vier RCTs wurden in die Metaanalyse einbezogen. Insgesamt ging die berufsbezogene Unterstützung von Krebspatienten im Vergleich zur Regelversorgung mit deutlich besseren PCS-Scores [physische Lebensqualität] (standardisierte Mittelwertdifferenz [SMD]=0,22; 95-%-KI, 0,06–0,37; P=0,005) und verminderten Lebensqualität-Schmerz-Scores (SMD=−0,16; 95-%-KI, −0.31–0; P=0,04) einher, zeigte aber keinen klar erkennbaren Einfluss auf die MCS-Scores (psychische Lebensqualität] (SMD=0; 95-%-KI, −0,28–0,28; P=0,98), den Zeitpunkt der Rückkehr an den Arbeitsplatz (SMD=−0,78; 95-%-KI, −2,71–1,14; P=0,43) oder die Arbeitsfähigkeits-Scores (SMD=−0,01; 95-%-KI, −0,16–9,09; P=0,13) und die Arbeitseinschränkung (SMD=0,12; 95-%-KI, −0,16–0,40; P=0,41).

Schlussfolgerung Die berufsbezogene unterstützende Rehabilitation ist möglicherweise eine wirksame Maßnahme zur Verbesserung der Lebensqualität von Krebspatienten.



Publication History

Received: 05 January 2022

Accepted: 03 January 2023

Article published online:
09 February 2023

© 2023. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
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