The Effect of Cycloplegia on the Biometer for Optical Low-coherence Reflectometry

Abstract

Purpose The aim of this study was to compare the biometric measurements and different formulas for calculating intraocular lens (IOL) power by using the Lenstar LS900 biometer for optical low-coherence reflectometry before and after induction of cycloplegia in the adult population.

Materials and Methods In this cross-sectional study, 168 eyes of 168 healthy volunteers aged 40 – 86 years (59.22 ± 11.57) were included. Biometric measurements, including axial length (AL), anterior chamber depth (ACD), keratometry (K1 and K2), and white-to-white (WTW) were compared using a Lenstar LS900 optical biometer before and after induction of cycloplegia with 1% cyclopentolate. The IOL power was also compared using six different formulas (Barrett Universal II, Haigis, SRK/T, Hoffer Q, Holladay, and SRK-II) for the AcrySof MA60AC IOL before and after induction of cycloplegia.

Results There were no statistically significant differences in AL, K1 and K2, or WTW measurements before and after induction of cycloplegia. There was a significant increase only in ACD from the biometric parameters after the induction of cycloplegia (p < 0.05). Despite this change, there were no significant changes in IOL power calculations using the six different formulas before and after induction of cycloplegia.

Conclusions This study demonstrated that IOL power measurements using the Lenstar LS900 can be performed after cycloplegia.

Zusammenfassung

Zweck Das Ziel dieser Studie ist es, die biometrischen Messungen und verschiedene Formeln zur Berechnung der Intraokularlinsenstärke unter Verwendung des optischen Low-Coherence-Reflektometrie-Biometers Lenstar LS900 vor und nach der Induktion von Zykloplegie bei Erwachsenen zu vergleichen.

Material und Methoden In diese Querschnittsstudie wurden 168 Augen von 168 gesunden Freiwilligen im Alter von 40 – 86 Jahren (59,22 ± 11,57) eingeschlossen. Biometrische Messungen, einschl. Achsenlänge (AL), Vorderkammertiefe (ACD), Keratometrie (K1, K2) und Weiß-zu-Weiß (WTW), wurden mit einem optischen Biometriegerät Lenstar LS900 vor und nach Induktion einer Zykloplegie mit Cyclopentolat 1% verglichen. Die Stärke der Intraokularlinse (IOL) wurde auch unter Verwendung von 6 verschiedenen Formeln (Barrett Universal II, Haigis, SRK/T, Hoffer Q, Holladay und SRK-II) für die Intraokularlinse AcrySof MA60AC vor und nach Induktion der Zykloplegie verglichen.

Ergebnisse Es gab keine statistisch signifikanten Unterschiede in Achslänge, Keratometrie (K1 und K2) oder Weiß-zu-Weiß-Messungen vor und nach Induktion der Zykloplegie. Es gab nur einen signifikanten Anstieg der ACD aus den biometrischen Parametern nach der Induktion der Zykloplegie (p < 0,05). Trotz dieser Änderung gab es keine signifikanten Änderungen bei den Berechnungen der IOL-Stärke unter Verwendung der 6 verschiedenen Formeln vor und nach der Induktion der Zykloplegie.

Schlussfolgerungen Diese Studie zeigte, dass IOL-Stärkemessungen mit dem Lenstar LS900 nach Zykloplegie durchgeführt werden können.

Conclusion Box

Already known:

• As shown in previous studies, ACD from biometric measurements increases after the use of mydriatic agents, but the IOL power calculation is not affected by this increase when the SRK/T formula is used.

Newly described:

• In particular, different results have been reported in studies examining new generation multivariable formulas after pupil dilation.

• The current study suggests that the Lenstar LS900, an optical low-coherence reflectometry biometry device, can also be used after cycloplegia with the Barrett Universal II, SRK/T, Hoffer-Q, Haigis, Holladay, and SRK-II formulas in adults.

Key words

cataract - refractive surgery - physiological optics

Schlüsselwörter

Katarakt - refraktive Chirurgie - physiologische Optik

Publication History

Received: 29 September 2022

Accepted: 23 December 2022

Accepted Manuscript online:
03 January 2023

Article published online:
29 March 2023

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