Download PDF
Zeitschrift für Phytotherapie 2023; 44(05): 201-206
DOI: 10.1055/a-1979-5416
Forschung

Ätherische Öle als Hemmer des bakteriellen Quorum Sensings

Essential oils as inhibitors of bacterial quorum sensing
Matthias F. Melzig
1   Institut für Pharmazie, Freie Universität Berlin
› Author Affiliations
› Further Information
    Permissions and Reprints

Zusammenfassung

Antibiotikaresistente Krankheitserreger stellen eine zunehmende Gefahr bei der Behandlung von Infektionen dar. Insbesondere Biofilme als Bakteriengemeinschaften rücken hier in den Fokus, da gegen sie klassische Antibiotika zumeist wirkungslos sind. Eine wichtige Rolle bei der Biofilmbildung spielt das Quorum Sensing, das durch ätherische Öle gestört werden kann.

Abstract

Pathogens that are resistant to antibiotics pose an increasing danger to the treatment of infections. A case in point are biofilms as bacterial communities which are resistant to classic antibiotics. Quorum sensing plays an important role in the biofilm formation. This process can be inhibited by essential oils.



Publication History

Article published online:
17 October 2023

© 2023. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

  • Literatur

  • 1 Rüschemeyer G. Die Sprache der Bakterien. Berlin: Schering Stiftung; 2018
    Google Scholar
  • 2 Reichling J. Anti-biofilm and virulence factor-reducing activities of essential oil components as a possible option for bacterial infection control. Planta Med 2020; 86: 520-537
    Article in Thieme ConnectPubMedGoogle Scholar
  • 3 Zhang D, Gan RY, Zhang JR. et al. Antivirulence properties and related mechanisms of spice essential oils: A comprehensive review. Compr Rev Food Sci Food Saf 2020; 19: 1018-1055
    CrossrefPubMedGoogle Scholar
  • 4 Li TT, Wang DF, Liu N. et al. Inhibition of quorum sensing-controlled virulence factors and biofilm formation in Pseudomonas fluorescens by cinnamaldehyde. Int J Food Microbiol 2018; 269: 98-106
    CrossrefPubMedGoogle Scholar
  • 5 Swamy MK, Akhtar MS, Sinniah UR. Antimicrobial properties of plant essential oils against human pathogens and their mode of action: An updated review. Evid Based Complement Alternat Med 2016; 2016: 3012462
    CrossrefPubMedGoogle Scholar
  • 6 Freires IA, Denny C, Benso B. et al. Antibacterial activity of essential oils and their isolated constituents against cariogenic bacteria: A systematic review. Molecules 2015; 20: 7329-7358
    CrossrefPubMedGoogle Scholar
  • 7 Yanakiev S. Effects of cinnamon (Cinnamomum spp.) in dentistry: A review. Molecules 2020; 25: 4184
    CrossrefPubMedGoogle Scholar
  • 8 Luciardi MC, Blázquez MA, Alberto MR. et al. Grapefruit essential oils inhibit quorum sensing of Pseudomonas aeruginosa . Food Sci Technol Int 2020; 26: 231-241
    CrossrefPubMedGoogle Scholar
  • 9 Camele I, Elshafie HS, Caputo L, De Feo V. Anti-quorum sensing and antimicrobial effect of Mediterranean plant essential oils against phytopathogenic bacteria. Front Microbiol 2019; 10: 2619
    CrossrefPubMedGoogle Scholar