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Horm Metab Res 2022; 54(11): 731-735
DOI: 10.1055/a-1951-1646
Review

Rhabdomyolysis Caused by Hypothyroidism: Research Progress

Qingju Zhou
1   Department of Health Management Center, Chongqing General Hospital, Chongqing, China
,
Bin Li
1   Department of Health Management Center, Chongqing General Hospital, Chongqing, China
,
Xin Tian
2   Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Neurology, Chongqing, China
› Author Affiliations Funding Information This work was supported by grants from the National Natural Science Foundation of China (82001378) and the Joint project of Chongqing Health Commission and Science and Technology Bureau (2019ZY023458).
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Abstract

Rhabdomyolysis (RM) refers to the clinical syndrome caused by the release of intracellular substances into the extracellular fluid and blood circulation after rhabdomyocyte destruction due to various etiologies. In severe cases, RM can lead to life-threatening conditions such as acute kidney injury. Hypothyroidism is a rare cause of RM that can lead to missed diagnosis or misdiagnosis, and the condition worsens in the absence of timely and effective treatment. Herein, reported cases of RM caused by hypothyroidism are summarized, and clinical diagnosis and treatment recommendations are proposed to facilitate early identification and treatment of the disease.

Key words

hypothyroidism - thyroid - rhabdomyolysis - creatine kinase - acute kidney injury


Publication History

Received: 17 April 2022

Accepted after revision: 16 September 2022

Article published online:
10 November 2022

© 2022. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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