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DOI: 10.1055/a-1931-3761
„Negativdruck-Lungenödem“ und „alveoläre Hämorrhagie“ als Komplikationen einer oberen Atemwegsobstruktion
Negative-pressure pulmonary edema and alveolar hemorrhage are potentially life-threatening complications of upper airway obstruction![](https://www.thieme-connect.de/media/pneumologie/202307/lookinside/thumbnails/10-1055-a-1931-3761-1.jpg)
Widmung
Diesen Artikel widmen wir unserem Lehrer Prof. Dr. Peter Wichert, ehemaliger Direktor der Medizinischen Poliklinik Marburg, zum 87. Geburtstag. Er hat uns für die Physiologie begeistert.
Zusammenfassung
Negativdruck-Lungenödem und alveoläre Hämorrhagie sind lebensbedrohliche Komplikationen infolge einer akuten oberen Atemwegsobstruktion. Durch die Obstruktion im Larynx-/Pharynbereich kommt es zu hohen negativen Intrapleuraldrucken, die sich, durch unterschiedliche Faktoren bedingt, auf die Integrität der alveolo-kapillären Membran auswirken. In der Übersichtsarbeit werden klinische Symptome, Ätiologie, die Pathophysiologie sowie die therapeutischen Optionen beschrieben. Ziel ist es, den Kliniker mit den Krankheitsbildern und den Komplikationen vertraut zu machen.
Abstract
Negative pressure pulmonary edema and alveolar hemorrhage are potentially life-threatening complications after relief of upper airway obstruction. The laryngeal-pharyngeal obstruction results in high negative intrapleural pressures. The increased intrapleural pressures affect the integrity of the alveolo-capillary membrane due to various factors. This review describes clinical symptoms, etiologic factors, pathophysiology and treatment strategies associated with each of these factors. The aim of this review is to equip clinicians with the knowledge base necessary to identify patients at increased risk for negative pressure pulmonary edema and alveolar hemorrhage.
Schlüsselwörter
obere Atemwegsobstruktion - diffuse alveoläre Hämorrhagie - obstruktive Schlafapnoe - Negativdruck - LungenödemKeywords
upper airway obstruction - diffuse alveolar hemorrhage - obstructive sleep apnea - negative pressure - pulmonary edemaPublikationsverlauf
Eingereicht: 01. Juni 2022
Angenommen nach Revision: 23. August 2022
Artikel online veröffentlicht:
15. November 2022
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