Medullary Thyroid Carcinoma presenting as an Incidentaloma on Gallium-68-PSMA-PET/CT – Systematic Literature Review and Case Report

Introduction

The prostate-specific membrane antigen (PSMA) is established in imaging and treatment of prostate cancer, especially in recurrent disease. PSMA is a membrane-bound glycoprotein with the function of a glutamic acid releasing carboxypeptidase enzyme, which is biologically expressed by the prostate and among others, proximal renal tubule cells, small intestine, central and peripheral nervous system [1]. Positrone Emission Tomography (PET)/ Computed Tomography (CT) imaging with Gallium (Ga)-68 in prostate cancer has its benefits in demonstrating the extent of the current disease and in preceding possible therapy with radionuclides like Lutetium (Lu)-177 and also the feasibility of intraoperative probe-assisted detection and localization of respective lesions.

Publication History

Received: 08 October 2020

Accepted after revision: 07 July 2022

Article published online:
11 August 2022

• References

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