Synlett 2022; 33(11): 1003-1010
DOI: 10.1055/a-1801-4696
synpacts

Synthesis of Carbonyl Compounds by Gold-Catalyzed Carbonylation Reactions

Yanwei Cao
a   Department of Chemistry, Fudan University, Shanghai 200438, P. R. of China
b   State Key Laboratory for Oxo Synthesis and Selective Oxidation (OSSO), Lanzhou Institute of Chemical Physics (LICP), Chinese Academy of Sciences (CAS), Lanzhou 730000, P. R. of China
,
Lin He
b   State Key Laboratory for Oxo Synthesis and Selective Oxidation (OSSO), Lanzhou Institute of Chemical Physics (LICP), Chinese Academy of Sciences (CAS), Lanzhou 730000, P. R. of China
› Author Affiliations
This work was supported by the National Natural Science Foundation of China (Grant Numbers 21802151 and 21972152) and the China Postdoctoral Science Foundation (Grant Number 2020M681146).


Abstract

In recent years, carbonylation reactions has experienced rapid progress and has become the essential and efficient strategies for the large-scale preparation of carbonyl compounds. Although palladium, rhodium, iridium, ruthenium, and cobalt are the dominating catalysis in carbonylation reactions, the gold has emerged as a selectable catalysis in some specific carbonylation reactions in the past two decades. Both homogeneous and heterogeneous gold catalysis have been studied in carbonylation reactions. Herein, we briefly reviewed the history of gold-catalyzed carbonylation reactions, including carbonylation of olefins, methanol, and amines. It also highlights our recent works on synergistic Au/Cu-catalyzed oxidative carbonylation of amines.

1 Introduction

2 Carbonylation of Olefins

3 Carbonylation of Methanol

4 Carbonylation of Amines

4.1 Gold Catalysis

4.2 Bimetallic Au–M catalysis

5 Conclusion and Outlook



Publication History

Received: 02 March 2022

Accepted after revision: 17 March 2022

Accepted Manuscript online:
17 March 2022

Article published online:
25 April 2022

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