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Horm Metab Res 2022; 54(03): 131-144
DOI: 10.1055/a-1767-5581
Review

The Impact of Bariatric Surgery on Bone Health: State of the Art and New Recognized Links

Fernando Mendonça
1   Serviço de Endocrinologia, Diabetes e Metabolismo, Centro Hospitalar e Universitário de S. João, Porto, Portugal
2   Faculdade de Medicina da Universidade do Porto, Porto, Portugal
,
Raquel Soares
2   Faculdade de Medicina da Universidade do Porto, Porto, Portugal
3   Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal
4   Departamento de Biomedicina, Faculdade de Medicina da Universidade do Porto, Porto, Portugal
,
Davide Carvalho
1   Serviço de Endocrinologia, Diabetes e Metabolismo, Centro Hospitalar e Universitário de S. João, Porto, Portugal
2   Faculdade de Medicina da Universidade do Porto, Porto, Portugal
3   Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal
,
Paula Freitas
1   Serviço de Endocrinologia, Diabetes e Metabolismo, Centro Hospitalar e Universitário de S. João, Porto, Portugal
2   Faculdade de Medicina da Universidade do Porto, Porto, Portugal
3   Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal
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Abstract

Bariatric surgery (BS) is the most effective therapy for severe obesity, which improves several comorbidities (such as diabetes, hypertension, dyslipidemia, among others) and results in marked weight loss. Despite these consensual beneficial effects, sleeve gastrectomy and Roux-en-Y gastric bypass (the two main bariatric techniques) have also been associated with changes in bone metabolism and progressive bone loss. The objective of this literature review is to examine the impact of bariatric surgery on bone and its main metabolic links, and to analyze the latest findings regarding the risk of fracture among patients submitted to bariatric surgery.

Key words

bariatric surgery - bone - sleeve gastrectomy - Roux-en-Y gastric bypass - fractures


Publication History

Received: 23 November 2021

Accepted after revision: 26 January 2022

Article published online:
11 March 2022

© 2022. Thieme. All rights reserved.

Georg Thieme Verlag
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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