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Aktuelle Kardiologie 2022; 11(02): 147-153
DOI: 10.1055/a-1693-2284
Kurzübersicht

Die polyvaskuläre Erkrankung – eine Übersicht über die Datenlage und Managementstrategien

The Polyvascular Disease – an Overview of the State of Knowledge and Management Strategies
Fabian Linden
1   Innere Medizin III: Kardiologie, Angiologie und Pneumologie, Universitätsklinikum Heidelberg Zentrum für Innere Medizin, Heidelberg, Deutschland
,
Norbert Frey
1   Innere Medizin III: Kardiologie, Angiologie und Pneumologie, Universitätsklinikum Heidelberg Zentrum für Innere Medizin, Heidelberg, Deutschland
,
Christian Erbel
1   Innere Medizin III: Kardiologie, Angiologie und Pneumologie, Universitätsklinikum Heidelberg Zentrum für Innere Medizin, Heidelberg, Deutschland
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Zusammenfassung

Als die polyvaskuläre Erkrankung (PVE) wird eine relevante Atherosklerose in 2 oder mehr Gefäßregionen bezeichnet. Die möglichen Gefäßregionen sind die Koronarien, zerebrovaskuläre und periphere Gefäße, welche häufig gleichzeitig betroffen sind. Dieses Patientenkollektiv hat ein relevant erhöhtes Risiko für zukünftige kardiovaskuläre Ereignisse und Letalität und sollte eine intensive Primär- und Sekundärprävention erhalten. Neue individuelle Therapiestrategien beinhalten intensivierte antithrombotische und lipidsenkende Maßnahmen und die optimale Einstellung eines Diabetes mellitus. Zur interventionellen Versorgung bei häufig hohem OP-Risiko steht ein breites Spektrum in allen Gefäßgebieten zur Verfügung.

Abstract

Polyvascular disease (PVD) is defined as relevant atherosclerosis in two or more vascular regions. The possible vascular regions are the coronary, cerebrovascular and peripheral vessels, which are often affected simultaneously. This patient population has a relevant increased risk for future cardiovascular events and mortality and should receive intensive primary and secondary prevention. New individual therapeutic strategies include intensified antithrombotic and lipid-lowering measures and optimal management of diabetes mellitus. A broad spectrum of interventional care is available in all vascular areas, often with a high risk of surgery.

Was ist wichtig?

  • Die Reduktion der Lebenserwartung von Patienten mit KHK oder PAVK ist besonders hoch, wenn atherosklerotische Läsionen in verschiedenen Gefäßregionen vorliegen (polyvaskuläre Erkrankung).

  • Diese Patienten bedürfen gezielter präventiver Maßnahmen einschließlich einer präventiv wirksamen Medikation zur Einstellung der Risikofaktoren.

  • Eine zentrale Rolle in der Therapie der polyvaskulären Erkrankung kommt dem intensivierten antithrombotischen, lipidsenkenden und antidiabetischen Management zu.

Schlüsselwörter

polyvaskuläre Erkrankung - kardiovaskuläre Prognose - präventive Maßnahmen - Risikofaktoren

Keywords

polyvascular disease - cardiovascular prognosis - preventative measures - risk factors


Publikationsverlauf

Artikel online veröffentlicht:
12. April 2022

© 2022. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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