Autoimmungastritis

Die Autoimmungastritis (AIG) ist eine chronische immunvermittelte Entzündung der Magenkorpus/-fundusschleimhaut, die zur progressiven Atrophie der oxyntischen Magendrüsen (AOM) und deren konsekutiven Funktionsverlust führt. Mögliche klinische Folgen der AIG sind Eisenmangelanämie, perniziöse Anämie, neuroendokrine Tumoren des Magens (gNET) und das Magenkarzinom. Dieser Beitrag bietet eine Übersicht interdisziplinärer Aspekte zur Diagnostik und Therapie der AIG.

Abstract

Autoimmune gastritis (AIG) is a chronic immune-mediated inflammation of the gastric corpus/fundus mucosa leading to progressive atrophy of the oxyntic gastric glands (AOM) and their consecutive loss of function. Possible clinical consequences of AIG include iron deficiency anemia, pernicious anemia, gastric neuroendocrine tumors (gNET), and gastric adenocarcinoma. This article provides a review of interdisciplinary aspects of the diagnosis and treatment of AIG.

Schlüsselwörter

Autoimmungastritis - Eisenmangelanämie - perniziöse Anämie - neuroendokrine Tumoren des Magens (gNET) - Magenkarzinom

Key words

autoimmune gastritis - iron deficiency anemia - pernicious anemia - gastric neuroendocrine tumors - gastric cancer

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