Psychosoziale Folgen von Quarantänemaßnahmen bei schwerwiegenden Coronavirus-Ausbrüchen: ein Rapid Review

Zusammenfassung

Ziel der Studie Zusammenschau von Evidenz über psychosoziale Folgen von Quarantänemaßnahmen bei schwerwiegenden Coronavirus-Ausbrüchen vor COVID-19. Entsprechende Erkenntnisse liefern wichtige Bezugspunkte zur COVID-19-Pandemie.

Methodik Suche in der MEDLINE-Datenbank nach relevanten Studien bei SARS-CoV- und MERS-CoV-Ausbrüchen.

Ergebnisse Insgesamt 13 selektierte Studien beschreiben konsistent psychosoziale Folgen von Quarantänemaßnahmen, darunter Depressivität, Ängstlichkeit, Wut, Stress, posttraumatische Belastung, soziale Isolation, Einsamkeit und Stigmatisierung. Determinanten waren u. a. die Dauer der Quarantäne und Einkommensverluste. Tätige im Gesundheitswesen waren eine besonders vulnerable Gruppe.

Schlussfolgerung Quarantänemaßnahmen bei schwerwiegenden Coronavirus-Ausbrüchen haben negative Konsequenzen für die psychosoziale Gesundheit. Präventions- und Interventionsansätze zur Reduktion der psychosozialen Folgen sollten integraler Bestandteil des Krisenmanagements unter Pandemiebedingungen sein.

Abstract

Objective Review of the evidence on the psychosocial impact of quarantine measures during serious coronavirus outbreaks before COVID-19. Such information is highly relevant in regard to the COVID-19 pandemic.

Methods Search of the MEDLINE database for relevant studies related to SARS-CoV and MERS-CoV outbreaks.

Results Across 13 identified studies, quarantine measures were consistently associated with negative psychosocial outcomes, including depressive symptoms, anxiety, anger, stress, posttraumatic stress, social isolation, loneliness and stigmatization. Determinants comprised duration of quarantine measures and income losses. Health care workers constituted a particularly vulnerable group.

Conclusion Quarantine measures during serious coronavirus outbreaks have extensive negative consequences for mental health. Prevention and intervention approaches to attenuate the psychosocial impact should be an integral component of crisis response during pandemic conditions.

Schlüsselwörter

Coronavirus - COVID-19 - Pandemie - psychosoziale Gesundheit - Quarantäne

Keywords

coronavirus - COVID-19 - pandemic - mental health - quarantine

^* geteilte Erstautorenschaft

• Literatur

• 1 Hui DS. et al. The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health – The latest 2019 novel coronavirus outbreak in Wuhan, China. Int J Infect Dis 2020; 91: 264-266
• 2 World Health Organization. WHO Director-Generalʼs opening remarks at the media briefing on COVID-19. Im Internet: https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---11-march-2020 Stand: 12.04.2020
• 3 Johns Hopkins University, Coronavirus Resource Center. COVID-19 United States Cases by County. Im Internet: https://coronavirus.jhu.edu/us-map Stand: 16.04.2020
• 4 Robert Koch-Institut. Risikobewertung zu COVID-19. Im Internet: https://www.rki.de/DE/Content/InfAZ/N/Neuartiges_Coronavirus/Risikobewertung.html Stand: 12.04.2020
• 5 Robert Koch-Institut. COVID-19: Fallzahlen in Deutschland und weltweit. Im Internet: https://www.rki.de/DE/Content/InfAZ/N/Neuartiges_Coronavirus/Fallzahlen.html Stand: 16.04.2020
• 6 Bundesregierung Deutschland. Besprechung der Bundeskanzlerin mit den Regierungschefinnen und Regierungschefs der Länder. Die Bundeskanzlerin und die Regierungschefinnen und Regierungschefs der Länder fassen am 22. März 2020 folgenden Beschluss. (22.03.2020). Im Internet: https://www.bundesregierung.de/breg-de/themen/coronavirus/besprechung-der-bundeskanzlerin-mit-den-regierungschefinnen-und-regierungschefs-der-laender-1733248 Stand: 12.04.2020
• 7 Bundesamt für Justiz. Gesetz zur Verhütung und Bekämpfung von Infektionskrankheiten beim Menschen (Infektionsschutzgesetz). § 30 Quarantäne (IfSG). https://www.gesetze-im-internet.de/ifsg/__30.html
• 8 Williams AW, Ware JE, Donald CA. A Model of Mental Health, Life Events, and Social Supports Applicable to General Populations. Journal of Health and Social Behavior 1981; 22: 324
• 9 Luhmann M, Hawkley LC. Age differences in loneliness from late adolescence to oldest old age. Dev Psychol 2016; 52: 943-959
• 10 Rico-Uribe LA, Caballero FF, Martín-María N. et al. Association of loneliness with all-cause mortality: A meta-analysis. PLoS ONE 2018; 13 e0190033 DOI: 10.1371/journal.pone.0190033.
• 11 Hawkley LC, Cacioppo JT. Loneliness matters: a theoretical and empirical review of consequences and mechanisms. Ann Behav Med 2010; 40: 218-227
• 12 World Health Organization. Summary of probable SARS cases with onset of illness from 1 November 2002 to 31 July 2003. Im Internet: http://www.who.int/csr/sars/country/table2004_04_21/en/ Stand: 04.04.2020
• 13 Robert Koch-Institut. Informationen des RKI zu MERS-Coronavirus. Im Internet: https://www.rki.de/DE/Content/InfAZ/M/MERS_Coronavirus/MERS-CoV.html Stand: 04.04.2020
• 14 World Health Organization. Middle East respiratory syndrome coronavirus (MERS-CoV). Im Internet: https://www.who.int/emergencies/mers-cov/en/ Stand: 04.04.2020
• 15 World Health Organization. Mental health and psychosocial considerations during the COVID-19 outbreak. (18.03.2020). Im Internet: https://www.who.int/docs/default-source/coronaviruse/mental-health-considerations.pdf
• 16 Tricco AC, Antony J, Zarin W. et al. A scoping review of rapid review methods. BMC Med 2015; 13: 224
• 17 Jeong H, Yim HW, Song Y-J. et al. Mental health status of people isolated due to Middle East Respiratory Syndrome. Epidemiol Health 2016; 38 e2016048 DOI: 10.4178/epih.e2016048.
• 18 Liu X, Kakade M, Fuller CJ. et al. Depression after exposure to stressful events: lessons learned from the severe acute respiratory syndrome epidemic. Compr Psychiatry 2012; 53: 15-23
• 19 Mihashi M, Otsubo Y, Yinjuan X. et al. Predictive factors of psychological disorder development during recovery following SARS outbreak. Health Psychol 2009; 28: 91-100
• 20 Reynolds DL, Garay JR, Deamond SL. et al. Understanding, compliance and psychological impact of the SARS quarantine experience. Epidemiol Infect 2008; 136: 997-1007
• 21 Wu P, Fang Y, Guan Z. et al. The psychological impact of the SARS epidemic on hospital employees in China: exposure, risk perception, and altruistic acceptance of risk. Can J Psychiatry 2009; 54: 302-311
• 22 Bai Y, Lin C-C, Lin C-Y. et al. Survey of stress reactions among health care workers involved with the SARS outbreak. Psychiatr Serv 2004; 55: 1055-1057
• 23 Hawryluck L, Gold WL, Robinson S. et al. SARS control and psychological effects of quarantine, Toronto, Canada. Emerging Infect Dis 2004; 10: 1206-1212
• 24 Cava MA, Fay KE, Beanlands HJ. et al. The experience of quarantine for individuals affected by SARS in Toronto. Public Health Nurs 2005; 22: 398-406
• 25 Robertson E, Hershenfield K, Grace SL. et al. The psychosocial effects of being quarantined following exposure to SARS: a qualitative study of Toronto health care workers. Can J Psychiatry 2004; 49: 403-407
• 26 Maunder R, Hunter J, Vincent L. et al. The immediate psychological and occupational impact of the 2003 SARS outbreak in a teaching hospital. CMAJ 2003; 168: 1245-1251
• 27 DiGiovanni C, Conley J, Chiu D. et al. Factors influencing compliance with quarantine in Toronto during the 2003 SARS outbreak. Biosecur Bioterror 2004; 2: 265-272
• 28 Sprang G, Silman M. Posttraumatic stress disorder in parents and youth after health-related disasters. Disaster Med Public Health Prep 2013; 7: 105-110
• 29 Yoon M-K, Kim S-Y, Ko H-S. et al. System effectiveness of detection, brief intervention and refer to treatment for the people with post-traumatic emotional distress by MERS: a case report of community-based proactive intervention in South Korea. Int J Ment Health Syst 2016; 10: 51
• 30 Weiss DMC. The impact of event scale – revised. In: Wilson J, Keane T. eds. Assessing psychological trauma and PTSD. New York: Guilford; 1997
• 31 Craig TJ, van Natta PA. Recognition of depressed affect in hospitalized psychiatric patients: staff and patient perceptions. Dis Nerv Syst 1976; 37: 561-566
• 32 Cheng SKW, Wong CW, Tsang J. et al. Psychological distress and negative appraisals in survivors of severe acute respiratory syndrome (SARS). Psychol Med 2004; 34: 1187-1195
• 33 Cheng SKW, Sheng B, Lau KK. et al. Adjustment outcomes in Chinese patients following one-month recovery from severe acute respiratory syndrome in Hong Kong. J Nerv Ment Dis 2004; 192: 868-871
• 34 Sheng B, Cheng SKW, Lau KK. et al. The effects of disease severity, use of corticosteroids and social factors on neuropsychiatric complaints in severe acute respiratory syndrome (SARS) patients at acute and convalescent phases. Eur Psychiatry 2005; 20: 236-242
• 35 Angermeyer MC, Matschinger H, Schomerus G. Public attitudes towards people with depression in times of uncertainty: results from three population surveys in Germany. Soc Psychiatry Psychiatr Epidemiol 2013; 48: 1513-1518
• 36 Lee S, Chan LYY, Chau AMY. et al. The experience of SARS-related stigma at Amoy Gardens. Soc Sci Med 2005; 61: 2038-2046
• 37 Pappas G, Kiriaze IJ, Giannakis P. et al. Psychosocial consequences of infectious diseases. Clin Microbiol Infect 2009; 15: 743-747
• 38 Cava MA, Fay KE, Beanlands HJ. et al. Risk perception and compliance with quarantine during the SARS outbreak. J Nurs Scholarsh 2005; 37: 343-347
• 39 Person B, Sy F, Holton K. et al. Fear and stigma: the epidemic within the SARS outbreak. Emerging Infect Dis 2004; 10: 358-363
• 40 Krohne HW. Stress and coping theories. In: Krohne HW. ed. International Encyclopedia of the Social Behavioral Sciences. 22. Aufl.; 2002: 15163-15170
• 41 Wheaton B. Models for the Stress-Buffering Functions of Coping Resources. Journal of Health and Social Behavior 1985; 26: 352
• 42 Dalgard OS, Bjørk S, Tambs K. Social support, negative life events and mental health. Br J Psychiatry 1995; 166: 29-34
• 43 Löbner M, Pabst A, Stein J. et al. Computerized cognitive behavior therapy for patients with mild to moderately severe depression in primary care: A pragmatic cluster randomized controlled trial (@ktiv). J Affect Disord 2018; 238: 317-326
• 44 Stein J, Röhr S, Luck T. et al. Indikationen und Evidenz von international entwickelten Online-Coaches zur Intervention bei psychischen Erkrankungen – ein Meta-Review. Psychiat Prax 2018; 45: 7-15
• 45 Dong L, Bouey J. Public Mental Health Crisis during COVID-19 Pandemic, China. Emerging Infect Dis 2020; 26 DOI: 10.3201/eid2607.200407.
• 46 Fatke B, Hölzle P, Frank A. et al. Psychische Probleme in der Pandemie – Beobachtungen während der COVID-19-Krise. Dtsch Med Wochenschr 2020; DOI: 10.1055/a-1147-2889.
• 47 Shultz JM, Baingana F, Neria Y. The 2014 Ebola outbreak and mental health: current status and recommended response. JAMA 2015; 313: 567-568