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Exp Clin Endocrinol Diabetes 2020; 128(06/07): 428-431
DOI: 10.1055/a-1014-2510
Mini-Review

More Than Fever - Novel Concepts in the Regulation of Body Temperature by Thyroid Hormones

Jens Mittag
1   University of Lübeck, Center of Brain Behavior and Metabolism (CBBM), Lübeck, Germany
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Abstract

Thyroid hormone is well known for its profound effects on body temperature. This minireview summarizes the recent discoveries on the underlying mechanisms, including the role of the hormone’s central actions in the control of brown adipose tissue thermogenesis, its effect on browning of white adipose tissue, the possible involvement of thyroid hormone transporters, and the potential contribution of its downstream metabolites such as 3-iodothyronamine.

Key words

thyroid hormone receptor - brown fat - beige fat - fever - pyrexia - anapyrexia - thyronamine


Publication History

Received: 12 July 2019
Received: 05 September 2019

Accepted: 16 September 2019

Article published online:
25 October 2019

© Georg Thieme Verlag KG
Stuttgart · New York

 

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