Fortschr Röntgenstr
DOI: 10.1055/a-1001-2412
Oncologic Imaging
© Georg Thieme Verlag KG Stuttgart · New York

Update Regarding Imaging of Neuroendocrine Neoplasms

Article in several languages: English | deutsch
Jens Holger Figiel
1  Diagnostic & Interventional Radiology, University-Hospital of Giessen and Marburg Campus Marburg, Germany
,
Simon G. Viniol
1  Diagnostic & Interventional Radiology, University-Hospital of Giessen and Marburg Campus Marburg, Germany
,
Jannis Görlach
1  Diagnostic & Interventional Radiology, University-Hospital of Giessen and Marburg Campus Marburg, Germany
,
Anja Rinke
2  Department for Gastroenterology, University-Hospital of Giessen and Marburg Campus Marburg, Germany
,
Damiano Librizzi
3  Department for Nuclear Medicine, University-Hospital of Giessen and Marburg Campus Marburg, Germany
,
Andreas H. Mahnken
1  Diagnostic & Interventional Radiology, University-Hospital of Giessen and Marburg Campus Marburg, Germany
› Author Affiliations
Further Information

Publication History

13 April 2019

30 July 2019

Publication Date:
11 September 2019 (online)

Abstract

Background Neuroendocrine neoplasms (NEN) are a heterogeneous group of tumors characterized by the expression of typical proteins. A wide range of morphological and functional imaging methods is required in order to adequately assess the course of the disease and to optimally treat the patient. The spectrum of indications ranges from the detection of small primary tumors to the documentation of the metastasis pattern and the assessment of the suitability for certain invasive or noninvasive therapy methods. The exact recording and quantification of findings is indispensable.

Methods This article is based on a comprehensive literature search on the different aspects of neuroendocrine neoplasm imaging.

Results This article is intended to provide an overview of the available imaging procedures with their respective advantages and disadvantages for diagnostics and their value for the follow-up of neuroendocrine neoplasms. Recommendations for examination protocols, typical image findings, and an outlook regarding future developments are presented.

Key Points:

  • Neuroendocrine neoplasms are relatively rare and represent a complex and multiform disease group. Even in metastatic disease, long-term progression-free survival is not uncommon.

  • Diagnostics in neuroendocrine neoplasms use a wide range of complementary morphological and functional imaging methods.

  • Adequate selection of the imaging method, examination planning and preparation of the patient are essential for exact staging and reliable follow-up.

Citation Format

  • Figiel JH, Viniol SG, Görlach J et al. Update Regarding Imaging of Neuroendocrine Neoplasms. Fortschr Röntgenstr 2019; DOI: 10.1055/a-1001-2412