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DOI: 10.1055/a-0991-7585
The Potential Applications of Hyaluronic Acid Hydrogels in Biomedicine
Publication History
received 12 May 2019
accepted 05 August 2019
Publication Date:
25 September 2019 (online)
![](https://www.thieme-connect.de/media/drugres/202001/lookinside/thumbnails/2019-05-1826_10-1055-a-0991-7585-1.jpg)
Abstract
Hyaluronic acid (HA) is widely used in the biomedicine due to its biocompatibility, biodegradability, and nontoxic properties. It is crucial for cell signaling role during morphogenesis, inflammation, and wound repair. After hydrogel formation, HA easily is converted to elastic sheets in order to use in preclinical and clinical applications. In addition, HA-derived hydrogels are easily used as vectors for cell and medication in tissue repairing and regenerative medicine. Moreover, in comparison with other polymers, HA -based hydrogels play a key role in in cellular behavior, including stem cell differentiation. The current paper reviews both basic concepts and recent advances in the development of HA-based hydrogels for biomedical applications.
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