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Nervenheilkunde 2020; 39(04): 206-212
DOI: 10.1055/a-0976-0558
Schwerpunkt
© Georg Thieme Verlag KG Stuttgart · New York

Aphasie nach ischämischem Hirninfarkt im links anterioren Thalamus

Fallbericht mit Literaturübersicht
Merve Fritsch
1   Klinik für Neurologie, Charité – Universitätsmedizin Berlin
,
Hellmuth Obrig∗
2   Klinik für Kognitive Neurologie, Medizinische Fakultät der Universität Leipzig und Max Planck Institut für Kognitions- und Neurowissenschaften Leipzig
,
Thomas Krause∗
3   Center for Stroke Research Berlin, Charité – Universitätsmedizin Berlin
,
Kersten Villringer∗
3   Center for Stroke Research Berlin, Charité – Universitätsmedizin Berlin
,
Fabian Klostermann∗
1   Klinik für Neurologie, Charité – Universitätsmedizin Berlin
,
Christian H. Nolte∗
1   Klinik für Neurologie, Charité – Universitätsmedizin Berlin
3   Center for Stroke Research Berlin, Charité – Universitätsmedizin Berlin
› Author Affiliations
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Publication History

Publication Date:
02 April 2020 (online)

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ZUSAMMENFASSUNG

Aphasie ist ein typisches Symptom links fronto-temporaler Läsionen. Nicht selten werden aphasische Symptome jedoch auch nach subkortikalen Läsionen z. B. im Thalamus beschrieben. Als Ursache für aphasische Symptome bei Thalamusschädigungen vermutet man die Störung eines thalamo-kortikalen Sprachnetzwerkes. Die Rolle des Thalamus in Sprachfunktionen wird in einer Rekrutierung sprachrelevanter, kortikaler Areale im Sinne einer Monitorfunktion vermutet. Wir berichten über einen 72-jährigen Patienten, der nach einem isolierten, links-anterioren Thalamusinfarkt eine expressiv betonte Aphasie gezeigt hat, und geben einen Überblick zu pathophysiologischen Konzepten.

Abstract

Aphasia is a language disturbance typically associated with left fronto-temporal lesions. However, aphasic symptoms can also be seen after subcortical lesions, for example in the thalamus. Thalamic aphasia is thought to occur after disruption of a thalamo-cortical language networks. The thalamus is considered to act as a monitor, engaging specific cortical areas need for language functions. We report on a 72-year old male patient who presented with aphasia following a left-anterior ischemic stroke of the thalamus and present a review of the relevant literature.

 

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