Drug Res (Stuttg)
DOI: 10.1055/a-0945-1469
Review
© Georg Thieme Verlag KG Stuttgart · New York

Application of Carbon Nanotubes in Breast Cancer Therapy

Mahdis Tajabadi
Student of Research Committee, Islamic Azad University of Medical Science, Tehran, Iran
› Author Affiliations
Further Information

Publication History

received 17 December 2018

accepted 28 May 2019

Publication Date:
28 June 2019 (online)

Abstract

Conjugated single-walled carbon nanotubes (SWNT) have been shown to be promising in cancer-targeted accumulation and is biocompatible, easily excreted, and possesses little toxicity. The present study aims at reviewing the recent advancements in carbon nanotubes especially SWNT for improving the treatment of breast cancer. Nanotube drug delivery system is a potential high efficacy therapy with minimum side effects for future tumor therapy with low doses of drug.

 
  • References

  • 1 Mourouti N, Panagiotakos DB, Kotteas EA. et al. Optimizing diet and nutrition for cancer survivors: A review. Maturitas 2017; 105: 33-36
  • 2 DeSantis C, Siegel R, Bandi P. et al. Breast cancer statistics, 2011. CA: A Cancer Journal for Clinicians 2011; 61: 408-418
  • 3 Valastyan S, Weinberg RA. Tumor metastasis: Molecular insights and evolving paradigms. Cell 2011; 147: 275-292
  • 4 Lorzadeh N, Kazemirad S, Lorzadeh M. et al. Comparison of the effect of oral and intravenous fluid therapy on women with oligohydramnios. Res J Obstet Gynecol 2008; 1: 25-29
  • 5 Fidler IJ. The pathogenesis of cancer metastasis: The ‘seed and soil’ hypothesis revisited. Nature Reviews Cancer 2003; 3: 453
  • 6 Nguyen DX, Bos PD, Massagué J. Metastasis: From dissemination to organ-specific colonization. Nature Reviews Cancer 2009; 9: 274
  • 7 Kam NWS, O'Connell M, Wisdom JA. et al. Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction. Proceedings of the National Academy of Sciences 2005; 102: 11600-11605
  • 8 Akbariasbagh F, Lorzadeh N, Azmoodeh A. et al. Association among diameter and volume of follicles, oocyte maturity, and competence in intracytoplasmic sperm injection cycles. Minerva Ginecologica 2015; 67: 397-403
  • 9 Lu S, Panchapakesan B. Optically driven nanotube actuators. Nanotechnology 2005; 16: 2548
  • 10 Lu S, Panchapakesan B. Nanotube micro-optomechanical actuators. Applied Physics Letters 2006; 88: 253107
  • 11 Lu S, Panchapakesan B. Photomechanical responses of carbon nanotube/polymer actuators. Nanotechnology 2007; 18: 305502
  • 12 Haddon RC. Carbon nanotubes. ACS Publications; 2002
  • 13 Milne W, Teo K, Amaratunga G. et al. Carbon nanotubes as field emission sources. Journal of Materials Chemistry 2004; 14: 933-943
  • 14 Berger J, Reist M, Mayer JM. et al. Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications. European Journal of Pharmaceutics and Biopharmaceutics 2004; 57: 19-34
  • 15 Ericson LM, Fan H, Peng H. et al. Macroscopic, neat, single-walled carbon nanotube fibers. Science 2004; 305: 1447-1450
  • 16 Martin CR, Kohli P. The emerging field of nanotube biotechnology. Nature Reviews Drug Discovery 2003; 2: 29
  • 17 Bianco A, Prato M. Can carbon nanotubes be considered useful tools for biological applications?. Advanced Materials 2003; 15: 1765-1768
  • 18 Kam NWS, Dai H. Carbon nanotubes as intracellular protein transporters: Generality and biological functionality. Journal of the American Chemical Society 2005; 127: 6021-6026
  • 19 Mehra NK, Mishra V, Jain N. A review of ligand tethered surface engineered carbon nanotubes. Biomaterials 2014; 35: 1267-1283
  • 20 Mehra NK, Jain NK. Multifunctional hybrid-carbon nanotubes: New horizon in drug delivery and targeting. Journal of Drug Targeting 2016; 24: 294-308
  • 21 Lorzadeh N, Ghasem Nejad A, Mohmad Pour J. The Effect of metformin on outcome of Intrauterine insemination (IUI) in insulin non-resistant infertile women with polycystic ovarian syndrome. The Iranian. Journal of Obstetrics, Gynecology and Infertility 2014; 17: 1-11
  • 22 Roldo M, Fatouros DG. Biomedical applications of carbon nanotubes. Annual Reports Section" C"(Physical Chemistry) 2013; 109: 10-35
  • 23 Casais-Molina ML, Cab C, Canto G. et al. Carbon Nanomaterials for Breast Cancer Treatment %J Journal of Nanomaterials. 2018; 2018: 9, doi:10.1155/2018/2058613 [published Online First: Epub Date]
  • 24 Bianco A, Kostarelos K, Prato M. Applications of carbon nanotubes in drug delivery. Current Opinion in Chemical Biology 2005; 9: 674-679
  • 25 Wu W, Wieckowski S, Pastorin G. et al. Targeted delivery of amphotericin B to cells by using functionalized carbon nanotubes. Angewandte Chemie International Edition 2005; 44: 6358-6362
  • 26 Pastorin G, Wu W, Wieckowski S. et al. Double functionalisation of carbon nanotubes for multimodal drug delivery. Chemical Communications 2006; 11: 1182-1184
  • 27 Sanginario A, Miccoli B, Demarchi D. Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment. Biosensors 2017; 7 9 DOI: 10.3390/bios7010009 [published. Online First: Epub Date]
  • 28 Fahrenholtz CD, Hadimani M, King SB. et al. Targeting breast cancer with sugar-coated carbon nanotubes. Nanomedicine (London, England) 2015; 10: 2481-2497, doi:10.2217/NNM.15.90 [published Online First: Epub Date]
  • 29 Chen RJ, Bangsaruntip S, Drouvalakis KA. et al. Noncovalent functionalization of carbon nanotubes for highly specific electronic biosensors. Proceedings of the National Academy of Sciences 2003; 100: 4984-4989
  • 30 Radomski A, Jurasz P, Alonso-Escolano D. et al. Nanoparticle-induced platelet aggregation and vascular thrombosis. British Journal of Pharmacology 2005; 146: 882-893
  • 31 Narayan RJ, Jin C, Menegazzo N. et al. Nanoporous hard carbon membranes for medical applications. Journal of Nanoscience and Nanotechnology 2007; 7: 1486-1493
  • 32 Shao N, Lu S, Wickstrom E. et al. Integrated molecular targeting of IGF1R and HER2 surface receptors and destruction of breast cancer cells using single wall carbon nanotubes. Nanotechnology 2007; 18: 315101
  • 33 Browne BC, Eustace AJ, Kennedy S. et al. Evaluation of IGF1R and phosphorylated IGF1R as targets in HER2-positive breast cancer cell lines and tumours. Breast Cancer Research and Treatment 2012; 136: 717-727
  • 34 Chakravarty P, Marches R, Zimmerman NS. et al. Thermal ablation of tumor cells with antibody-functionalized single-walled carbon nanotubes. Proceedings of the National Academy of Sciences 2008; 105: 8697-8702
  • 35 McDevitt MR, Chattopadhyay D, Kappel BJ. et al. Tumor targeting with antibody-functionalized, radiolabeled carbon nanotubes. Journal of Nuclear Medicine 2007; 48: 1180-1189
  • 36 Raza K, Kumar D, Kiran C. et al. Conjugation of Docetaxel with Multiwalled Carbon Nanotubes and Codelivery with Piperine: Implications on Pharmacokinetic Profile and Anticancer Activity. Molecular Pharmaceutics 2016; 13: 2423-2432. doi:10.1021/acs.molpharmaceut.6b00183 [published Online First: Epub Date]
  • 37 Son KH, Hong JH, Lee JW. Carbon nanotubes as cancer therapeutic carriers and mediators. International Journal of Nanomedicine 2016; 11: 5163
  • 38 Liu J, Appaix F, Bibari O. et al. Control of neuronal network organization by chemical surface functionalization of multi-walled carbon nanotube arrays. Nanotechnology 2011; 22: 195101
  • 39 MacDonald RA, Laurenzi BF, Viswanathan G. et al. Collagen–carbon nanotube composite materials as scaffolds in tissue engineering. Journal of Biomedical Materials Research Part A: An Official Journal of The Society for Biomaterials, The Japanese Society for Biomaterials, and The Australian Society for Biomaterials and the Korean Society for Biomaterials 2005; 74: 489-496
  • 40 Tonelli FM, Santos AK, Gomes KN. et al. Carbon nanotube interaction with extracellular matrix proteins producing scaffolds for tissue engineering. International Journal of Nanomedicine 2012; 7: 4511
  • 41 Riaz M, Fulati A, Amin G. et al. Buckling and elastic stability of vertical ZnO nanotubes and nanorods. Journal of Applied Physics 2009; 106: 034309
  • 42 Teker K, Wickstrom E, Panchapakesan B. Biomolecular tuning of electronic transport properties of carbon nanotubes via antibody functionalization. IEEE Sensors Journal 2006; 6: 1422-1428
  • 43 Tajallaie-Asl F, Mardani M, Shahsavari S. et al. Menstruation phytotherapy according to iran ethnobotanical sources. J. Pharm. Sci. & Res 2017; 9: 986-990
  • 44 Singh S, Mehra NK, Jain N. Development and characterization of the paclitaxel loaded riboflavin and thiamine conjugated carbon nanotubes for cancer treatment. Pharmaceutical Research 2016; 33: 1769-1781
  • 45 Al Faraj A, Shaik AS, Halwani R. et al. Magnetic targeting and delivery of drug-loaded SWCNTs theranostic nanoprobes to lung metastasis in breast cancer animal model: Noninvasive monitoring using magnetic resonance imaging. Molecular Imaging and Biology 2016; 18: 315-324
  • 46 Mashal A, Sitharaman B, Li X. et al. Toward carbon-nanotube-based theranostic agents for microwave detection and treatment of breast cancer: Enhanced dielectric and heating response of tissue-mimicking materials. IEEE Transactions on Biomedical Engineering 2010; 57: 1831-1834
  • 47 Dineshkumar B, Krishnakumar K, Bhatt A. et al. Single-walled and multi-walled carbon nanotubes based drug delivery system: Cancer therapy: A review. Indian Journal of Cancer 2015; 52: 262
  • 48 Xiao Y, Gao X, Taratula O. et al. Anti-HER2 IgY antibody-functionalized single-walled carbon nanotubes for detection and selective destruction of breast cancer cells. BMC cancer 2009; 9: 351
  • 49 Yu S, Zhang Y, Chen L. et al. Antitumor effects of carbon nanotube-drug complex against human breast cancer cells. Experimental and therapeutic medicine 2018; 16: 1103-1110. doi:10.3892/etm.2018.6334 [published Online First: Epub Date]|
  • 50 Gajewicz A, Rasulev B, Dinadayalane TC. et al. Advancing risk assessment of engineered nanomaterials: Application of computational approaches. Advanced Drug Delivery Reviews 2012; 64: 1663-1693