Int J Sports Med 2019; 40(08): 487-497
DOI: 10.1055/a-0938-4415
Review
© Georg Thieme Verlag KG Stuttgart · New York

Recommendations in Post-exercise Hypotension: Concerns, Best Practices and Interpretation

Leandro Campos de Brito
1   Exercise Hemodynamic Laboratory, School of Physical Education and Sport, University of Sao Paulo, Sao Paulo, Brazil
,
Rafael Yokoyama Fecchio
1   Exercise Hemodynamic Laboratory, School of Physical Education and Sport, University of Sao Paulo, Sao Paulo, Brazil
,
Tiago Peçanha
2   Applied Physiology & Nutrition Research Group; Laboratory of Assessment and Conditioning in Rheumathology, Clinical Hospital HCFMUSP, Faculty of Medicine, University of Sao Paulo, Sao Paulo, Brazil
,
Aluisio Lima
1   Exercise Hemodynamic Laboratory, School of Physical Education and Sport, University of Sao Paulo, Sao Paulo, Brazil
,
John Halliwill
3   Department of Human Physiology, University of Oregon, Eugene, United States
,
Claudia Lucia de Moraes Forjaz
1   Exercise Hemodynamic Laboratory, School of Physical Education and Sport, University of Sao Paulo, Sao Paulo, Brazil
› Author Affiliations
Further Information

Publication History



accepted 13 May 2019

Publication Date:
09 July 2019 (online)

Abstract

Post-exercise hypotension (PEH) is a clinically relevant phenomenon that has been widely investigated. However, the characteristics of study designs, such as familiarization to blood pressure measurements, duration of PEH assessments or strategies to analyze PEH present discrepancies across studies. Thus identifying key points to standardize across PEH studies is necessary to help researchers to build stronger study designs, to facilitate comparisons across studies, and to avoid misinterpretations of results. The goal of this narrative review of methods used in PEH studies was therefore to gather and find possible influencers in the characteristics of study design and strategies to analyze blood pressure. Data found in this review suggest that PEH studies should have at least two familiarization screening visits, and should assess blood pressure for at least 20 min, but preferably for 120 min, during recovery from exercise. Another important aspect is the strategy to analyze PEH, which may lead to different interpretations. This information should guide a priori study design decisions.

 
  • References

  • 1 Kenney MJ, Seals DR. Postexercise hypotension. Key features, mechanisms, and clinical significance. Hypertension 1993; 22: 653-664
  • 2 Brito LC, Queiroz AC, Forjaz CL. Influence of population and exercise protocol characteristics on hemodynamic determinants of post-aerobic exercise hypotension. Braz J Med Biol Res 2014; 47: 626-636
  • 3 Halliwill JR, Buck TM, Lacewell AN, Romero SA. Postexercise hypotension and sustained postexercise vasodilatation: what happens after we exercise?. Exp Physiol 2013; 98: 7-18
  • 4 Luttrell MJ, Halliwill JR. Recovery from exercise: vulnerable state, window of opportunity, or crystal ball?. Front Physiol 2015; 6: 204
  • 5 Carpio-Rivera E, Moncada-Jimenez J, Salazar-Rojas W, Solera-Herrera A. Acute effects of exercise on blood pressure: A Meta-analytic investigation. Arq Bras Cardiol 2016; 106: 422-433
  • 6 Casonatto J, Goessler KF, Cornelissen VA, Cardoso JR, Polito MD. The blood pressure-lowering effect of a single bout of resistance exercise: A systematic review and meta-analysis of randomised controlled trials. Eur J Prev Cardiol 2016; 23: 1700-1714
  • 7 Taylor-Tolbert NS, Dengel DR, Brown MD, McCole SD, Pratley RE, Ferrell RE, Hagberg JM. Ambulatory blood pressure after acute exercise in older men with essential hypertension. Am J Hypertens 2000; 13: 44-51
  • 8 Forjaz CL, Tinucci T, Ortega KC, Santaella DF, Mion Jr. D, Negrao CE. Factors affecting post-exercise hypotension in normotensive and hypertensive humans. Blood Press Monit 2000; 5: 255-262
  • 9 Wallace JP, Bogle PG, King BA, Krasnoff JB, Jastremski CA. A comparison of 24-h average blood pressures and blood pressure load following exercise. Am J Hypertens 1997; 10: 728-734
  • 10 Wallace JP, Bogle PG, King BA, Krasnoff JB, Jastremski CA. The magnitude and duration of ambulatory blood pressure reduction following acute exercise. J Hum Hypertens 1999; 13: 361-366
  • 11 Cronin P, Ryan F, Coughlan M. Undertaking a literature review: a step-by-step approach. Br J Nurs 2008; 17: 38-43
  • 12 Harriss DJ, Macsween A, Atkinson G. Standards for ethics in sport and exercise science research: 2018 update. Int J Sports Med 2017; 38: 1126-1131
  • 13 Stolt M, Sjonell G, Astrom H, Hansson L. The reliability of auscultatory measurement of arterial blood pressure. A comparison of the standard and a new methodology. Am J Hypertens 1990; 3: 697-703
  • 14 Clark EG, Glock CY, Schweitzer MD, Vought RL. Studies in hypertension. II. Variability of daily blood pressure measurements in the same individuals over a 3-week period. J Chronic Dis 1956; 4: 469-476
  • 15 Rosner B, Polk BF. The instability of blood pressure variability over time. J Chronic Dis 1981; 34: 135-139
  • 16 Malachias MVB, Paulo Cesar Veiga Jardim PCVJ, Almeida FA, Lima EJ, Feitosa 7th GS. Brazilian Guideline of Arterial Hypertension: Chapter 7 - Pharmacological Treatment. Arq Bras Cardiol 2016; 107: 35-43
  • 17 Mancia G, Fagard R, Narkiewicz K, Redon J, Zanchetti A, Bohm M, Christiaens T, Cifkova R, De Backer G, Dominiczak A, Galderisi M, Grobbee DE, Jaarsma T, Kirchhof P, Kjeldsen SE, Laurent S, Manolis AJ, Nilsson PM, Ruilope LM, Schmieder RE, Sirnes PA, Sleight P, Viigimaa M, Waeber B, Zannad F, Task Force M. 2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens 2013; 31: 1281-1357
  • 18 Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo Jr. JL, Jones DW, Materson BJ, Oparil S, Wright Jr. JT, Roccella EJ. Seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure.. Hypertension 2003; 42: 1206-1252
  • 19 Pearce KA, Grimm Jr. RH, Rao S, Svendsen K, Liebson PR, Neaton JD, Ensrud K. Population-derived comparisons of ambulatory and office blood pressures. Implications for the determination of usual blood pressure and the concept of white coat hypertension. Arch Intern Med 1992; 152: 750-756
  • 20 Andre JL, Petit JC, Gueguen R, Deschamps JP. [Variability of arterial pressure and heart rate measured at two periods of 15 min to 15 days intervals]. Arch Mal Coeur Vaiss 1987; 80: 1005-1010
  • 21 Bovet P, Gervasoni JP, Ross AG, Mkamba M, Mtasiwa DM, Lengeler C, Burnier M, Paccaud F. Assessing the prevalence of hypertension in populations: are we doing it right?. J Hypertens 2003; 21: 509-517
  • 22 Angadi SS, Bhammar DM, Gaesser GA. Postexercise hypotension after continuous, aerobic interval, and sprint interval exercise. J Strength Cond Res 2015; 29: 2888-2893
  • 23 Augeri AL, Tsongalis GJ, Van Heest JL, Maresh CM, Thompson PD, Pescatello LS. The endothelial nitric oxide synthase -786 T>C polymorphism and the exercise-induced blood pressure and nitric oxide responses among men with elevated blood pressure. Atherosclerosis 2009; 204: e28-e34
  • 24 Bonsu B, Terblanche E. The training and detraining effect of high-intensity interval training on post-exercise hypotension in young overweight/obese women. Eur J Appl Physiol 2016; 116: 77-84
  • 25 Cavalcante BR, Ritti-Dias RM, Soares AH, Lima AH, Correia MA, De Matos LD, Gobbi F, Leicht AS, Wolosker N, Cucato GG. A single bout of arm crank exercise promotes positive emotions and post exercise hypotension in patients with symptomatic peripheral artery disease. Eur J Vasc Endovasc Surg 2017; 53: 223-228
  • 26 Cunha F, Midgley AW, Pescatello L, Soares PP, Farinatti P. Acute hypotensive response to continuous and accumulated isocaloric aerobic bouts. Int J Sports Med 2016; 37: 855-862
  • 27 Dantas TC, Farias Junior LF, Frazao DT, Silva PH, Sousa Junior AE, Costa IB, Ritti-Dias RM, Forjaz CL, Duhamel TA, Costa EC. A single session of low-volume high-intensity interval exercise reduces ambulatory blood pressure in normotensive males. J Strength Cond Res 2017; 31: 2263-2269
  • 28 Endo MY, Kajimoto C, Yamada M, Miura A, Hayashi N, Koga S, Fukuba Y. Acute effect of oral water intake during exercise on post-exercise hypotension. Eur J Clin Nutr 2012; 66: 1208-1213
  • 29 Endo MY, Shimada K, Miura A, Fukuba Y. Peripheral and central vascular conductance influence on post-exercise hypotension. J Physiol Anthropol 2012; 31: 32
  • 30 Gagnon D, Lynn AG, Binder K, Boushel RC, Kenny GP. Mean arterial pressure following prolonged exercise in the heat: influence of training status and fluid replacement. Scand J Med Sci Sports 2012; 22: e99-e107
  • 31 Goessler KF, Cornelissen VA, de Oliveira EM, de FMG, Polito MD. ACE polymorphisms and the acute response of blood pressure to a walk in medicated hypertensive patients. J Renin Angiotensin Aldosterone Syst 2015; 16: 720-729
  • 32 Halliwill JR, Minson CT, Joyner MJ. Effect of systemic nitric oxide synthase inhibition on postexercise hypotension in humans. J Appl Physiol (1985) 2000; 89: 1830-1836
  • 33 Halliwill JR, Taylor JA, Eckberg DL. Impaired sympathetic vascular regulation in humans after acute dynamic exercise. J Physiol 1996; 495 (Pt 1) 279-288
  • 34 Harvey PJ, Morris BL, Kubo T, Picton PE, Su WS, Notarius CF, Floras JS. Hemodynamic after-effects of acute dynamic exercise in sedentary normotensive postmenopausal women. J Hypertens 2005; 23: 285-292
  • 35 Heffernan KS, Collier SR, Kelly EE, Jae SY, Fernhall B. Arterial stiffness and baroreflex sensitivity following bouts of aerobic and resistance exercise. Int J Sports Med 2007; 28: 197-203
  • 36 Jones HG K, Edwards B, Atkinson G. Is the magnitude of acute post-exercise hypotension mediated by exercise intensity or total work done?. Eur J Appl Physiol 2007; 102: 33-40
  • 37 Lacombe SP, Goodman JM, Spragg CM, Liu S, Thomas SG. Interval and continuous exercise elicit equivalent postexercise hypotension in prehypertensive men, despite differences in regulation. Appl Physiol Nutr Metab 2011; 36: 881-891
  • 38 Lehmkuhl LA, Park S, Zakutansky D, Jastremski CA, Wallace JP. Reproducibility of postexercise ambulatory blood pressure in Stage I hypertension. J Hum Hypertens 2005; 19: 589-595
  • 39 Liu S, Goodman J, Nolan R, Lacombe S, Thomas SG. Blood pressure responses to acute and chronic exercise are related in prehypertension. Med Sci Sports Exerc 2012; 44: 1644-1652
  • 40 Lockwood JM, Pricher MP, Wilkins BW, Holowatz LA, Halliwill JR. Postexercise hypotension is not explained by a prostaglandin-dependent peripheral vasodilation. J Appl Physiol (1985) 2005; 98: 447-453
  • 41 McCord JL, Beasley JM, Halliwill JR. H2-receptor-mediated vasodilation contributes to postexercise hypotension. J Appl Physiol (1985) 2006; 100: 67-75
  • 42 Pricher MP, Holowatz LA, Williams JT, Lockwood JM, Halliwill JR. Regional hemodynamics during postexercise hypotension. I. Splanchnic and renal circulations. J Appl Physiol (1985) 2004; 97: 2065-2070
  • 43 Raine NM, Cable NT, George KP, Campbell IG. The influence of recovery posture on post-exercise hypotension in normotensive men. Med Sci Sports Exerc 2001; 33: 404-412
  • 44 Rossow L, Yan H, Fahs CA, Ranadive SM, Agiovlasitis S, Wilund KR, Baynard T, Fernhall B. Postexercise hypotension in an endurance-trained population of men and women following high-intensity interval and steady-state cycling. Am J Hypertens 2010; 23: 358-367
  • 45 Santaella DF, Araujo EA, Ortega KC, Tinucci T, Mion Jr. D, Negrao CE, de Moraes Forjaz CL. Aftereffects of exercise and relaxation on blood pressure. Clin J Sport Med 2006; 16: 341-347
  • 46 Santana HA, Moreira SR, Asano RY, Sales MM, Cordova C, Campbell CS, Espindola FS, Sposito AC, Nobrega OT, Simoes HG. Exercise intensity modulates nitric oxide and blood pressure responses in hypertensive older women. Aging Clin Exp Res 2013; 25: 43-48
  • 47 Wilkins BW, Minson CT, Halliwill JR. Regional hemodynamics during postexercise hypotension. II. Cutaneous circulation. J Appl Physiol (1985) 2004; 97: 2071-2076
  • 48 Collier SR, Diggle MD, Heffernan KS, Kelly EE, Tobin MM, Fernhall B. Changes in arterial distensibility and flow-mediated dilation after acute resistance vs. aerobic exercise. J Strength Cond Res 2010; 24: 2846-2852
  • 49 Dujic Z, Ivancev V, Valic Z, Bakovic D, Marinovic-Terzic I, Eterovic D, Wisloff U. Postexercise hypotension in moderately trained athletes after maximal exercise. Med Sci Sports Exerc 2006; 38: 318-322
  • 50 Figueiredo T, Willardson JM, Miranda H, Bentes CM, Reis VM, Simao R. Influence of load intensity on postexercise hypotension and heart rate variability after a strength training session. J Strength Cond Res 2015; 29: 2941-2948
  • 51 Franklin PJ, Green DJ, Cable NT. The influence of thermoregulatory mechanisms on post-exercise hypotension in humans. J Physiol 1993; 470: 231-241
  • 52 Mach C, Foster C, Brice G, Mikat RP, Porcari JP. Effect of exercise duration on postexercise hypotension. J Cardiopulm Rehabil 2005; 25: 366-369
  • 53 Azevedo LM, de Souza AC, Santos LE, Miguel Dos Santos R, de Fernandes MO, Almeida JA, Pardono E. Fractionated concurrent exercise throughout the day does not promote acute blood pressure benefits in hypertensive middle-aged women. Front Cardiovasc Med 2017; 4: 6
  • 54 Birk GK, Dawson EA, Batterham AM, Atkinson G, Cable T, Thijssen DH, Green DJ. Effects of exercise intensity on flow mediated dilation in healthy humans. Int J Sports Med 2013; 34: 409-414
  • 55 Brito Ade F, de Oliveira CV, Santos Mdo S, Santos Ada C. High-intensity exercise promotes postexercise hypotension greater than moderate intensity in elderly hypertensive individuals. Clin Physiol Funct Imaging 2014; 34: 126-132
  • 56 Carter 3rd R, Watenpaugh DE, Smith ML. Gender differences in cardiovascular regulation during recovery from exercise. J Appl Physiol (1985) 2001; 91: 1902-1907
  • 57 Ciolac EG, Guimaraes GV, VM DA, Bortolotto LA, Doria EL, Bocchi EA. Acute effects of continuous and interval aerobic exercise on 24-h ambulatory blood pressure in long-term treated hypertensive patients. Int J Cardiol 2009; 133: 381-387
  • 58 Coats AJ, Conway J, Isea JE, Pannarale G, Sleight P, Somers VK. Systemic and forearm vascular resistance changes after upright bicycle exercise in man. J Physiol 1989; 413: 289-298
  • 59 Dawson EA, Whyte GP, Black MA, Jones H, Hopkins N, Oxborough D, Gaze D, Shave RE, Wilson M, George KP, Green DJ. Changes in vascular and cardiac function after prolonged strenuous exercise in humans. J Appl Physiol (1985) 2008; 105: 1562-1568
  • 60 Esformes JI, Norman F, Sigley J, Birch KM. The influence of menstrual cycle phase upon postexercise hypotension. Med Sci Sports Exerc 2006; 38: 484-491
  • 61 Hamer M, Boutcher SH. Impact of moderate overweight and body composition on postexercise hemodynamic responses in healthy men. J Hum Hypertens 2006; 20: 612-617
  • 62 Keese F, Farinatti P, Pescatello L, Cunha FA, Monteiro WD. Aerobic exercise intensity influences hypotension following concurrent exercise sessions. Int J Sports Med 2012; 33: 148-153
  • 63 New KJ, Reilly ME, Templeton K, Ellis G, James PE, McEneny J, Penney M, Hooper J, Hullin D, Davies B, Bailey DM. Free radical-mediated lipid peroxidation and systemic nitric oxide bioavailability: implications for postexercise hemodynamics. Am J Hypertens 2013; 26: 126-134
  • 64 Notarius CF, Morris BL, Floras JS. Caffeine attenuates early post-exercise hypotension in middle-aged subjects. Am J Hypertens 2006; 19: 184-188
  • 65 Somers VK, Conway J, Coats A, Isea J, Sleight P. Postexercise hypotension is not sustained in normal and hypertensive humans. Hypertension 1991; 18: 211-215
  • 66 Souza AA, Silva RS, Silva TF, Tavares RL, Silva AS. Influence of different doses of coffee on post-exercise blood pressure response. Am J Cardiovasc Dis 2016; 6: 146-152
  • 67 Takahashi T, Hayano J, Okada A, Saitoh T, Kamiya A. Effects of the muscle pump and body posture on cardiovascular responses during recovery from cycle exercise. Eur J Appl Physiol 2005; 94: 576-583
  • 68 Takahashi T, Okada A, Saitoh T, Hayano J, Miyamoto Y. Difference in human cardiovascular response between upright and supine recovery from upright cycle exercise. Eur J Appl Physiol 2000; 81: 233-239
  • 69 Wilcox RG, Bennett T, Brown AM, Macdonald IA. Is exercise good for high blood pressure?. Br Med J (Clin Res Ed) 1982; 285: 767-769
  • 70 Pescatello LS, Franklin BA, Fagard R, Farquhar WB, Kelley GA, Ray CA. American College of Sports Medicine position stand. Exercise and hypertension. Med Sci Sports Exerc 2004; 36: 533-553
  • 71 Hecksteden A, Grutters T, Meyer T. Association between postexercise hypotension and long-term training-induced blood pressure reduction: a pilot study. Clin J Sport Med 2013; 23: 58-63
  • 72 Moreira SR, Cucato GG, Terra DF, Ritti-Dias RM. Acute blood pressure changes are related to chronic effects of resistance exercise in medicated hypertensives elderly women. Clin Physiol Funct Imaging 2014; 36: 242-248
  • 73 Costa EC, Dantas TC, de Farias Junior LF, Frazao DT, Prestes J, Moreira SR, Ritti-Dias RM, Tibana RA, Duhamel TA. Inter- and intra-individual analysis of post-exercise hypotension following a single bout of high-intensity interval exercise and continuous exercise: A pilot study. Int J Sports Med 2016; 37: 1038-1043
  • 74 Jones H, Pritchard C, George K, Edwards B, Atkinson G. The acute post-exercise response of blood pressure varies with time of day. Eur J Appl Physiol 2008; 104: 481-489
  • 75 Jones H, George K, Edwards B, Atkinson G. Effects of time of day on post-exercise blood pressure: circadian or sleep-related influences?. Chronobiol Int 2008; 25: 987-998
  • 76 Headley SA, Germain MJ, Milch CM, Buchholz MP, Coughlin MA, Pescatello LS. Immediate blood pressure-lowering effects of aerobic exercise among patients with chronic kidney disease. Nephrology (Carlton) 2008; 13: 601-606
  • 77 MacDonald JR, MacDougall JD, Hogben CD. The effects of exercise duration on post-exercise hypotension. J Hum Hypertens 2000; 14: 125-129
  • 78 MacDonald J, MacDougall J, Hogben C. The effects of exercise intensity on post exercise hypotension. J Hum Hypertens 1999; 13: 527-531
  • 79 Rezk CC, Marrache RC, Tinucci T, Mion Jr. D, Forjaz CL. Post-resistance exercise hypotension, hemodynamics, and heart rate variability: influence of exercise intensity. Eur J Appl Physiol 2006; 98: 105-112
  • 80 MacDonald JR, MacDougall JD, Hogben CD. The effects of exercising muscle mass on post exercise hypotension. J Hum Hypertens 2000; 14: 317-320
  • 81 Forjaz CL, Cardoso Jr. CG, Rezk CC, Santaella DF, Tinucci T. Postexercise hypotension and hemodynamics: the role of exercise intensity. J Sports Med Phys Fitness 2004; 44: 54-62
  • 82 Brandao Rondon MU, Alves MJ, Braga AM, Teixeira OT, Barretto AC, Krieger EM, Negrao CE. Postexercise blood pressure reduction in elderly hypertensive patients. J Am Coll Cardiol 2002; 39: 676-682
  • 83 Hagberg JM, Montain SJ, Martin 3rd WH. Blood pressure and hemodynamic responses after exercise in older hypertensives. J Appl Physiol (1985) 1987; 63: 270-276
  • 84 Cleroux J, Kouame N, Nadeau A, Coulombe D, Lacourciere Y. Aftereffects of exercise on regional and systemic hemodynamics in hypertension. Hypertension 1992; 19: 183-191
  • 85 Floras JS, Sinkey CA, Aylward PE, Seals DR, Thoren PN, Mark AL. Postexercise hypotension and sympathoinhibition in borderline hypertensive men. Hypertension 1989; 14: 28-35
  • 86 Forjaz CL, Ramires PR, Tinucci T, Ortega KC, Salomao HE, Ignes EC, Wajchenberg BL, Negrao CE, Mion Jr. D. Postexercise responses of muscle sympathetic nerve activity and blood flow to hyperinsulinemia in humans. J Appl Physiol (1985) 1999; 87: 824-829
  • 87 Queiroz AC, Gagliardi JF, Forjaz CL, Rezk CC. Clinic and ambulatory blood pressure responses after resistance exercise. J Strength Cond Res 2009; 23: 571-578
  • 88 Teixeira L, Ritti-Dias RM, Tinucci T, Mion Junior D, Forjaz CL. Post-concurrent exercise hemodynamics and cardiac autonomic modulation. Eur J Appl Physiol 2011; 111: 2069-2078
  • 89 Brito LC, Rezende RA, Mendes C, Silva-Junior ND, Tinucci T, Cipolla-Neto J, Forjaz CL. Separate aftereffects of morning and evening exercise on ambulatory blood pressure in pre-hypertensive men. J Sports Med Phys Fitness 2018; 58: 157-163
  • 90 Queiroz AC, Sousa JC, Cavalli AA, Silva Jr. ND, Costa LA, Tobaldini E, Montano N, Silva GV, Ortega K, Mion Jr. D, Tinucci T, Forjaz CL. Post-resistance exercise hemodynamic and autonomic responses: Comparison between normotensive and hypertensive men. Scand J Med Sci Sports 2015; 25: 486-494
  • 91 Pescatello LS, Fargo AE, Leach Jr. CN, Scherzer HH. Short-term effect of dynamic exercise on arterial blood pressure. Circulation 1991; 83: 1557-1561
  • 92 Wallace JP, Park S, Zakutansky DW, Lehmkuhl LA, Jastremski CA. Time of day to monitor ambulatory blood pressure affects the outcome. Blood Press Monit 2005; 10: 43-50
  • 93 Floras JS, Wesche J. Haemodynamic contributions to post-exercise hypotension in young adults with hypertension and rapid resting heart rates. J Hum Hypertens 1992; 6: 265-269
  • 94 Isea JE, Piepoli M, Adamopoulos S, Pannarale G, Sleight P, Coats AJ. Time course of haemodynamic changes after maximal exercise. Eur J Clin Invest 1994; 24: 824-829
  • 95 Gotshall RW, Aten LA, Yumikura S. Difference in the cardiovascular response to prolonged sitting in men and women. Can J Appl Physiol 1994; 19: 215-225
  • 96 Mark AL, Mancia G. Cardiopulmonary baroreflex in humans. In Rowell LB, Shepherd JT. (eds) Handbook of Physiology; New york: Oxford: 1996: 795-813
  • 97 Mancia G, Zanchetti A. One hundred years of auscultatory blood pressure: commemorating N.S. Korotkoff. J Hypertens 2005; 23: 1-2
  • 98 Aprile DC, Oneda B, Gusmao JL, Costa LA, Forjaz CL, Mion Jr. D, Tinucci T. Post-exercise hypotension is mediated by a decrease in sympathetic nerve activity in stages 2-3 CKD. Am J Nephrol 2016; 43: 206-212
  • 99 Bisquolo VA, Cardoso Jr. CG, Ortega KC, Gusmao JL, Tinucci T, Negrao CE, Wajchenberg BL, Mion Jr. D, Forjaz CL.. Previous exercise attenuates muscle sympathetic activity and increases blood flow during acute euglycemic hyperinsulinemia. J Appl Physiol (1985) 2005; 98: 866-871
  • 100 Headley S, Germain M, Wood R, Joubert J, Milch C, Evans E, Cornelius A, Brewer B, Taylor B, Pescatello LS. Blood pressure response to acute and chronic exercise in chronic kidney disease. Nephrology (Carlton) 2017; 22: 72-78
  • 101 McCord JL, Halliwill JR. H1 and H2 receptors mediate postexercise hyperemia in sedentary and endurance exercise-trained men and women. J Appl Physiol (1985) 2006; 101: 1693-1701
  • 102 van Montfrans GA. Oscillometric blood pressure measurement: progress and problems. Blood Press Monit 2001; 6: 287-290
  • 103 Cameron JD, Stevenson I, Reed E, McGrath BP, Dart AM, Kingwell BA. Accuracy of automated auscultatory blood pressure measurement during supine exercise and treadmill stress electrocardiogram-testing. Blood Press Monit 2004; 9: 269-275
  • 104 Gomides RS, Dias RM, Souza DR, Costa LA, Ortega KC, Mion Jr. D, Tinucci T, de Moraes Forjaz CL. Finger blood pressure during leg resistance exercise. Int J Sports Med 2010; 31: 590-595
  • 105 Fecchio RY, Chehuen M, Brito LC, Pecanha T, Queiroz ACC, de Moraes Forjaz CL. Reproducibility (reliability and agreement) of post-exercise hypotension. Int J Sports Med 2017; 38: 1029-1034
  • 106 Cucato GG, Chehuen Mda R, Ritti-Dias RM, Carvalho CR, Wolosker N, Saxton JM, Forjaz CL. Post-walking exercise hypotension in patients with intermittent claudication. Med Sci Sports Exerc 2015; 47: 460-467
  • 107 de Brito LC, Rezende RA, da Silva Junior ND, Tinucci T, Casarini DE, Cipolla-Neto J, Forjaz CL.. Post-exercise hypotension and its mechanisms differ after morning and evening exercise: A randomized crossover study. PLoS One 2015; 10: e0132458
  • 108 Legramante JM, Galante A, Massaro M, Attanasio A, Raimondi G, Pigozzi F, Iellamo F. Hemodynamic and autonomic correlates of postexercise hypotension in patients with mild hypertension. Am J Physiol Regul Integr Comp Physiol 2002; 282: R1037-R1043
  • 109 Queiroz AC, Kanegusuku H, Chehuen MR, Costa LA, Wallerstein LF, Dias da Silva VJ, Mello MT, Ugrinowitsch C, Forjaz CL. Cardiac work remains high after strength exercise in elderly. Int J Sports Med 2013; 34: 391-397
  • 110 Queiroz AC, Rezk CC, Teixeira L, Tinucci T, Mion D, Forjaz CL. Gender influence on post-resistance exercise hypotension and hemodynamics. Int J Sports Med 2013; 34: 939-944
  • 111 Queiroz AC, Sousa Jr. JC, Silva Jr. ND, Tobaldini E, Ortega KC, de Oliveira EM, Brum PC, Montano N, Mion Jr. D, Tinucci T, de Moraes Forjaz CL.. Captopril does not potentiate post-exercise hypotension: a randomized crossover study. Int J Sports Med 2017; 38: 270-277
  • 112 Terblanche E, Millen AM. The magnitude and duration of post-exercise hypotension after land and water exercises. Eur J Appl Physiol 2012; 112: 4111-4118
  • 113 Parati G, Ochoa JE, Lombardi C, Bilo G. Assessment and management of blood-pressure variability. Nat Rev Cardiol 2013; 10: 143-155
  • 114 Hadaegh F, Shafiee G, Hatami M, Azizi F. Systolic and diastolic blood pressure, mean arterial pressure and pulse pressure for prediction of cardiovascular events and mortality in a Middle Eastern population. Blood Press 2012; 21: 12-18
  • 115 Lima AH, Miranda AS, Correia MA, Soares AH, Cucato GG, Sobral Filho DC, Gomes SL, Ritti-Dias RM. Individual blood pressure responses to walking and resistance exercise in peripheral artery disease patients: Are the mean values describing what is happening?. J Vasc Nurs 2015; 33: 150-156
  • 116 Guyatt GH, Juniper EF, Walter SD, Griffith LE, Goldstein RS. Interpreting treatment effects in randomised trials. BMJ 1998; 316: 690-693
  • 117 Bouchard C, Blair SN, Church TS, Earnest CP, Hagberg JM, Hakkinen K, Jenkins NT, Karavirta L, Kraus WE, Leon AS, Rao DC, Sarzynski MA, Skinner JS, Slentz CA, Rankinen T. Adverse metabolic response to regular exercise: is it a rare or common occurrence?. PLoS One 2012; 7: e37887
  • 118 Swinton PA, Hemingway BS, Saunders B, Gualano B, Dolan E. A statistical framework to interpret individual response to intervention: Paving the way for personalized nutrition and exercise prescription. Front Nutr 2018; 5: 41
  • 119 Dos Santos ES, Asano RY, Filho IG, Lopes NL, Panelli P, Nascimento Dda C, Collier SR, Prestes J. Acute and chronic cardiovascular response to 16 weeks of combined eccentric or traditional resistance and aerobic training in elderly hypertensive women: a randomized controlled trial. J Strength Cond Res 2014; 28: 3073-3084
  • 120 Tibana RA, de Sousa NM, da Cunha Nascimento D, Pereira GB, Thomas SG, Balsamo S, Simoes HG, Prestes J. Correlation between acute and chronic 24-hour blood pressure response to resistance training in adult women. Int J Sports Med 2015; 36: 82-89