RSS-Feed abonnieren
DOI: 10.1055/a-0856-6845
Detachable string magnetically controlled capsule endoscopy for complete viewing of the esophagus and stomach
Publikationsverlauf
submitted 07. September 2018
accepted after revision 28. Januar 2019
Publikationsdatum:
01. März 2019 (online)
![](https://www.thieme-connect.de/media/endoscopy/201904/lookinside/thumbnails/17159_10-1055-a-0856-6845-1.jpg)
Abstract
Background Esophageal capsule endoscopy is reported to be insufficiently accurate to replace esophagogastroduodenoscopy (EGD) because the passage of the capsule through the esophagus is passive and precludes a thorough investigation. We developed a modified capsule endoscopy technique, called detachable string magnetically controlled capsule endoscopy (DS-MCE), and performed a pilot study to assess the feasibility and safety of this novel technique.
Methods 4 healthy volunteers and 21 patients with suspected esophageal disease first underwent DS-MCE followed by EGD within 1 week. Outcomes included technical success of DS-MCE, adverse events, discomfort, and diagnostic accuracy.
Results DS-MCE was successfully carried out in all 25 participants. No adverse events were observed. Mean overall discomfort score during DS-MCE was 0.96 (range 0 – 3). DS-MCE diagnoses were in accordance with EGD in all 25 participants. The per-patient sensitivity of DS-MCE for esophageal disease detection was 100 %. The accuracy of DS-MCE for grading esophageal varices and reflux esophagitis were 66.7 % and 100 %, respectively.
Conclusions DS-MCE was a feasible, safe, and well-tolerated method for viewing the esophagus and proceeding with gastric examination after string detachment.
* These authors contributed equally to this work.
-
References
- 1 McCarty TR, Afinogenova Y, Njei B. Use of wireless capsule endoscopy for the diagnosis and grading of esophageal varices in patients with portal hypertension: a systematic review and meta-Analysis. J Clin Gastroenterol 2017; 51: 174-182
- 2 Hosoe N, Naganuma M, Ogata H. Current status of capsule endoscopy through a whole digestive tract. Dig Endosc 2015; 27: 205-215
- 3 Ramirez FC, Shaukat MS, Young MA. et al. Feasibility and safety of string, wireless capsule endoscopy in the diagnosis of Barrett’s esophagus. Gastrointest Endosc 2005; 61: 741-746
- 4 Liao Z, Gao R, Xu C. et al. Sleeve string capsule endoscopy for real-time viewing of the esophagus: a pilot study (with video). Gastrointest Endosc 2009; 70: 201-209
- 5 Liao Z, Hou X, Lin-Hu EQ. et al. Accuracy of magnetically controlled capsule endoscopy, compared with conventional gastroscopy, in detection of gastric diseases. Clin Gastroenterol Hepatol 2016; 14: 1266-1273
- 6 Zou WB, Hou XH, Xin L. et al. Magnetic-controlled capsule endoscopy vs. gastroscopy for gastric diseases: a two-center self-controlled comparative trial. Endoscopy 2015; 47: 525-528
- 7 Armstrong D, Bennett JR, Blum AL. et al. The endoscopic assessment of esophagitis: a progress report on observer agreement. Gastroenterology 1996; 111: 85-92
- 8 de Franchis R. Updating consensus in portal hypertension: report of the Baveno III Consensus Workshop on definitions, methodology and therapeutic strategies in portal hypertension. J Hepatol 2000; 33: 846-852
- 9 de Franchis R, Eisen GM, Laine L. et al. Esophageal capsule endoscopy for screening and surveillance of esophageal varices in patients with portal hypertension. Hepatology 2008; 47: 1595-1603
- 10 Chen WS, Zhu LH, Li DZ. et al. String esophageal capsule endoscopy with real-time viewing improves visualization of the distal esophageal Z-line: a prospective, comparative study. Eur J Gastroenterol Hepatol 2014; 26: 309-312
- 11 Tziatzios G, Gkolfakis P, Dimitriadis GD. et al. Long-term effects of video capsule endoscopy in the management of obscure gastrointestinal bleeding. Ann Transl Med 2017; 5: 196
- 12 Ching HL, Hale MF, Kurien M. et al. Diagnostic yield of magnetically assisted capsule endoscopy versus gastroscopy in recurrent and refractory iron deficiency anemia. Endoscopy 2018; DOI: 10.1055/a-0750-5682.
- 13 Jiang X, Qian YY, Liu X. et al. Impact of magnetic steering on gastric transit time of a capsule endoscopy (with video). Gastrointest Endosc 2018; 88: 746-754