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Rofo 2018; 190(12): 1121-1130
DOI: 10.1055/a-0612-8006
Review
© Georg Thieme Verlag KG Stuttgart · New York

Magnetic Resonance Imaging of Adipose Tissue in Metabolic Dysfunction

MR-Bildgebung von Fettgewebe bei Stoffwechselstörungen
Daniela Franz
1   Institute for Diagnostic and Interventional Radiology, Technische Universität München, Fakultät für Medizin, Munich, Germany
,
Jan Syväri
1   Institute for Diagnostic and Interventional Radiology, Technische Universität München, Fakultät für Medizin, Munich, Germany
,
Dominik Weidlich
1   Institute for Diagnostic and Interventional Radiology, Technische Universität München, Fakultät für Medizin, Munich, Germany
,
Thomas Baum
2   Institute for Diagnostic and Interventional Neuroradiology, Technische Universität München, Fakultät für Medizin, Munich, Germany
,
Ernst J Rummeny
1   Institute for Diagnostic and Interventional Radiology, Technische Universität München, Fakultät für Medizin, Munich, Germany
,
Dimitrios C. Karampinos
1   Institute for Diagnostic and Interventional Radiology, Technische Universität München, Fakultät für Medizin, Munich, Germany
› Author Affiliations
Further Information

Publication History

02 November 2017

07 April 2018

Publication Date:
06 June 2018 (online)

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Abstract

Background Adipose tissue has become an increasingly important tissue target in medicine. It plays a central role in the storage and release of energy throughout the human body and has recently gained interest for its endocrinologic function. Magnetic resonance imaging (MRI) is an established method for quantitative direct evaluation of adipose tissue distribution, and is used increasingly as the modality of choice for metabolic phenotyping. The purpose of this review was the identification and presentation of the currently available literature on MRI of adipose tissue in metabolic dysfunction.

Method A PubMed (http://www.ncbi.nlm.nih.gov/pubmed) keyword search up to August 2017 without starting date limitation was performed and reference lists of relevant articles were searched.

Results and Conclusion MRI provides excellent tools for the evaluation of adipose tissue distribution and further characterization of the tissue. Standard as well as newly developed MRI techniques allow a risk stratification for the development of metabolic dysfunction and enable monitoring without the use of ionizing radiation or contrast material.

Key points 

  • Different types of adipose tissue play a crucial role in various types of metabolic dysfunction.

  • Magnetic resonance imaging (MRI) is an excellent tool for noninvasive adipose tissue evaluation with respect to distribution, composition and metabolic activity.

  • Both standard and newly developed MRI techniques can be used for risk stratification for the development of metabolic dysfunction and allow monitoring without the use of ionizing radiation or contrast material.

Citation Format

  • Franz D, Syväri J, Weidlich D et al. Magnetic Resonance Imaging of Adipose Tissue in Metabolic Dysfunction. Fortschr Röntgenstr 2018; 190: 1121 – 1130

Zusammenfassung

Hintergrund Fettgewebe rückt zunehmend in den Fokus der Medizin. Es spielt eine zentrale Rolle bei der Speicherung und Freisetzung von Energie im gesamten menschlichen Körper und hat aufgrund seiner endokrinologischen Funktion in letzter Zeit das Interesse der Wissenschaft geweckt. Die Magnetresonanztomografie (MRT) ist eine etablierte Methode zur quantitativen direkten Beurteilung der Fettgewebsverteilung und wird zunehmend als Methode der Wahl für die metabolische Phänotypisierung eingesetzt. Der Zweck dieser Übersichtsarbeit ist die Identifizierung und Darlegung der derzeit verfügbaren Literatur über die MRT von Fettgewebe bei Stoffwechselstörungen.

Methode Eine PubMed (http://www.ncbi.nlm.nih.gov/pubmed) Schlagwortsuche bis August 2017 ohne Einschränkung hinsichtlich des Startdatums wurde durchgeführt und Referenzlisten relevanter Artikel wurden durchsucht.

Ergebnisse und Schlussfolgerung Die MRT bietet hervorragende Möglichkeiten zur Beurteilung der Fettgewebsverteilung und zur weiteren Charakterisierung des Gewebes. Standard- sowie neu entwickelte MRT-Techniken erlauben eine Risikostratifizierung hinsichtlich der Entwicklung von Stoffwechselstörungen und ermöglichen ein weiteres Monitoring ohne den Einsatz von ionisierender Strahlung oder Kontrastmittel.

Kernaussagen 

  • Verschiedene Typen von Fettgewebe spielen bei Stoffwechselstörungen eine entscheidende Rolle.

  • Die Magnetresonanztomografie bietet hervorragende Möglichkeiten zur nicht-invasiven Evaluation von Fettgewebe hinsichtlich dessen Verteilung, Zusammensetzung und Stoffwechselaktivität.

  • Sowohl MRT-Standardtechniken als auch neu entwickelte Techniken erlauben die Risikostratifizierung bzgl. Stoffwechselstörungen und ermöglichen deren Monitoring ohne den Gebrauch von ionisierender Strahlung oder Kontrastmittel.

Key words

MR imaging - MR spectroscopy - adipose tissue - brown fat - metabolic disorders
 

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