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DOI: 10.1055/a-0574-4866
Die personalisierte Therapie beim Ovarialkarzinom
Publikationsverlauf
Publikationsdatum:
06. April 2018 (online)
![](https://www.thieme-connect.de/media/tumor/201803/lookinside/thumbnails/td-5744866_10-1055-a-0574-4866-1.jpg)
Zusammenfassung
Die Behandlung des epithelialen Ovarial-, Tuben- und Peritonealkarzinoms (epithelial ovarian cancer; EOC) fußt auf 3 Säulen, die in unterschiedlichem Maße individualisierte bzw. personalisierte Medizin inkludieren:
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Die Operation, die immer personalisiert, d. h. angepasst an den Allgemeinzustand und die Reserven der Patientin, sowie individualisiert, d. h. adaptiert an das Tumorwachstum und Befallsmuster, durchgeführt wird.
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Die Chemotherapie, die bis dato nicht individualisiert bezüglich der Tumorbiologie, wohl aber angepasst an die klinische Situation zumindest in der Rezidivtherapie unter verschiedenen Regimen, wie z. B. platin- und nicht platinhaltig, ausgewählt wird.
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Die neueren zielgerichteten Substanzen, mit denen noch mehr Hoffnung auf personalisierte Medizin sowie effektivere und nebenwirkungsärmere Therapieregime für die individuelle Patientin verbunden wird.
* Beide Autorinnen waren zu gleichen Teilen beteiligt.
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