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CC BY-NC-ND 4.0 · Rev Bras Ortop (Sao Paulo) 2020; 55(05): 551-556
DOI: 10.1016/j.rbo.2018.01.001
Artigo Original
Joelho

Efeito comparativo entre a infiltração de plasma rico em plaquetas e o uso de corticosteroides no tratamento de osteoartrite do joelho: Estudo clínico prospectivo e randomizado[*]

Article in several languages: português | English
Marianna Ribeiro de Menezes Freire 
1   Faculty of Medicine, Universidade Tiradentes (Unitmed), Aracaju, SE, Brazil
,
Philippe Mota Coutinho da Silva
1   Faculty of Medicine, Universidade Tiradentes (Unitmed), Aracaju, SE, Brazil
,
Arthur Rangel Azevedo
2   Instituto de Assistência Médica ao Servidor Público Estadual de São Paulo (Iamspe), São Paulo, SP, Brazil
,
Denison Santos Silva
3   Universidade Tiradentes (Unitmed), Aracaju, SE, Brazil
,
Ronald Bispo Barreto da Silva
3   Universidade Tiradentes (Unitmed), Aracaju, SE, Brazil
,
Juliana Cordeiro Cardoso
3   Universidade Tiradentes (Unitmed), Aracaju, SE, Brazil
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Resumo

Objetivo Analisar a eficácia do uso de plasma rico em plaquetas, obtido do sangue periférico e autólogo dos pacientes, na redução das queixas álgicas e melhoria funcional dos pacientes portadores de osteoartrite de joelhos, em comparação com o tratamento padrão com injeção de corticosteroides de depósito, como a triancilonola.

Métodos Os pacientes foram acompanhados clinicamente na consulta pré-infiltrativa, com avaliação quantitativa através das escalas Knee Society Score (KSS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), e Kellgren and Lawrence. Além disso, os pacientes foram reavaliados com as mesmas escalas após 1 mês e 6 meses de intervenção com 2,5 mL de acetato de triancinolona ou 5 mL de plasma rico em plaquetas. O estudo foi feito em 50 pacientes portadores de osteoartrite de joelhos atendidos no Centro de Especialidades Médicas, divididos em amostras equivalentes randomizadas para cada terapia.

Resultados No presente estudo, verificaram-se redução dos valores em escalas álgicas, como a WOMAC, e elevação das pontuações em escalas funcionais, como a KSS, evidenciadas em 180 dias após o uso de plasma rico em plaquetas, uma terapia feita a partir do sangue autólogo do paciente e com menos efeitos colaterais.

Conclusão Embora ambas as terapias com plasma rico em plaquetas e corticosteroides tenham se mostrado eficazes na redução das queixas álgicas e na recuperação funcional, houve diferença significativa entre as terapias aos 180 dias. De acordo com os resultados obtidos, no tratamento da osteoartrite do joelho, o plasma rico em plaquetas demonstrou efeitos mais duradouros em 180 dias.

Palavras-chave

osteoartrite - corticoterapia - plasma rico em plaquetas

* Trabalho desenvolvido no Centro de Especialidades Médicas da Universidade Tiradentes (Unitmed), Aracaju, SE, Brasil. Publicado Originalmente por Elsevier Editora Ltda.




Publication History

Received: 20 October 2017

Accepted: 04 January 2018

Article published online:
03 February 2020

© 2020. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Sociedade Brasileira de Ortopedia e Traumatologia. Published by Thieme Revinter Publicações Ltda
Rio de Janeiro, Brazil

 

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