CC BY-NC-ND 4.0 · International Journal of Epilepsy 2014; 01(01): 008-015
DOI: 10.1016/j.ijep.2014.05.004
Original Article
Thieme Medical and Scientific Publishers Private Ltd.

Study of quality of life in epilepsy patients with psychiatric co-morbidities using QOLIE-31

Gujjar Amruth
a   Department of Neurology, Bangalore Medical College & Research Institute, Bangalore 560001, Karnataka, India
,
Praveen-kumar Srikanteswara
a   Department of Neurology, Bangalore Medical College & Research Institute, Bangalore 560001, Karnataka, India
,
Boraiah Nataraju
a   Department of Neurology, Bangalore Medical College & Research Institute, Bangalore 560001, Karnataka, India
,
Pandiyan Kasturi
b   Department of Psychiatry, Bangalore Medical College & Research Institute, Bangalore 560001, Karnataka, India
› Author Affiliations

Subject Editor:
Further Information

Publication History

Received: 14 November 2013

Accepted: 25 May 2014

Publication Date:
04 May 2018 (online)

Abstract

Background Epilepsy is a neurological condition affecting both the sexes in all age groups and is associated with psychiatric co-morbid conditions. There is a paucity of available published data regarding psychiatric co-morbid conditions and quality of life in patients with Epilepsy (PWE) from developing countries.

Methods We evaluated the quality of life in 80 PWE, 80 with asthma (asthma control subjects: AC) and 80 normal healthy patients (normal control subjects: NC) using the QOLIE-31 item inventory.

Results Psychiatric co-morbid conditions are more common in PWE (32.50%) as compared to the AC (17.5%) and NC (7.5%). The quality of life in PWE was significantly lower when compared to control subjects and it was further low in the presence of co-morbid psychiatric disorders.

Conclusion Co-morbid psychiatric disorders should be identified and documented in PWE and treating these disorders apart from the control of seizures may significantly improve their quality of life.

 
  • References

  • 1 Trivedi MH, Kurian BT. Managing depressive disorders in PWE. Psychiatry 2007; 27-34
  • 2 Bragatti JA, Torres CM, Isolan GR, Bianchin MM. Psychiatric comorbidities of epilepsy: a review. J Neurol Neurophysiol. S2 2011
  • 3 Verrotti A, Cicconetti A, Scorrano B. et al. Epilepsy and suicide: pathogenesis, risk factors, and prevention. Neuropsychiatr Dis Treat 4 2008; 365-370
  • 4 Jones JE, Hermann BP, Barry JJ, Gilliam F, Kanner AM, Meador KJ. Clinical assessment of axis I psychiatric morbidity in chronic epilepsy: a multicentre investigation. J Neuropsychiatry Clin Neurosci 17 2005; 172-179
  • 5 Hesdorffer DC, Ishihara L, Mynepalli L, Webb DJ, Hauser WA. Epilepsy, suicidality and psychiatric disorders: a bidirectional association. Ann Neurol 72 2012; 184-191
  • 6 Concept of health and disease. In: Park K. Park's Textbook of Preventive and Social Medicine. 20th ed.. 2009. M/s Banarsidas Bhanot Publishers; Jabalpur: 12-48
  • 7 Jacob R, Tharyan P. Psychiatric co-morbidities and quality of life in PWE. Ger J Psychiatr 13 2010; 79-85
  • 8 Whatley AD, Diloro CK, Yeager K. Examining the relationships of depressive symptoms, stigma, social support and regimen specific support on quality of life in adult PWE. Health Educ Res 25 2010; 575-584
  • 9 Cramer JA, Perrine K, Devinsky O. et al. Development and cross cultural translations of a 31 item quality of life in epilepsy inventory. Epilepsia 39 1998; 81-88
  • 10 Sander JW. The epidemiology of epilepsy revisited. Curr Opin Neurol 16 2003; 165-170
  • 11 Titlic M, Basic S, Hajnsek S, Lusic I. Comorbidity psychiatric disorders in epilepsy: a 439 review of literature. Bratisl Lek Listy 110 2009; 105-109
  • 12 Bijl RV, Ravelli A, Van Zessen G. Prevalence of psychiatric disorder in the general population results of The Netherlands Mental Health Survey and Incidence Study (NEMESIS). Soc Psychiatry Psychiatr Epidemiol 33 1998; 587-595
  • 13 Shetty PH, Naik RK, Saroja AO, Punith K. Quality of life in patients with epilepsy in India. J Neurosci Rural Pract 2 2011; Jan-Jun 33-38
  • 14 Thomas SV, Sarma PS, Alexander M. et al. Epilepsy care in six Indian cities: a multistudy on management and service. J Neurol Sci 188 2001; 73-77
  • 15 Sinha A, Sanyal D, Mallik S, Sengupta P, Dasgupta S. Factors associated with quality of life of patients with epilepsy attending a tertiary care hospital in Kolkata, India. Neurol Asia 16 2011; 33-37
  • 16 Devinsky O, Vickrey BG, Cramer J. et al. Development of the quality of life in epilepsy inventory. Epilepsia 36 1995; 1089-1104
  • 17 Sheehan DV, Lecrubier Y. Mini International Neuropsychiatric Interview. 2009. University of South Florida College of Medicine; Thampa, USA:
  • 18 Katon W, Lozano P, Russo J, McCauley E, Richardson L, Bush T. The prevalence of DSM-IV anxiety and depressive disorders in youth with asthma compared with controls. J Adolesc Health 41 2007; 455-463
  • 19 Craske MG, Poulton R, Tsao JC, Plotkin D. Paths to panic disorder/agoraphobia: an exploratory analysis from age 3 to 21 in an unselected birth cohort. J Am Acad Child Adolesc Psychiatry 40 2001; 556-563
  • 20 Scott KM, Von Korff M, Alonso J. et al. Childhood adversity, early-onset depressive/anxiety disorders, and adult-onset asthma. Psychosom Med 70 2008; 1035-1043
  • 21 Hermann BP. The evolution of health related quality of life assessment in epilepsy. Qual Life Res 4 1995; 87-100
  • 22 Mendez MF, Cummings JL, Benson DF. Depression in epilepsy, significance and phenomenology. Arch Neurol 42 1986; Aug 766-770
  • 23 Strine TW, Kobau R, Chapman DP. et al. Psychological distress, comorbidities, and 479 health behaviors among U. S. adults with seizures: results from the 2002 National 480 Health Interview Survey. Epilepsia 46 2005; 1133-1139
  • 24 Gaitatzis A, Caroll K, Majeed A, Sander JW. The epidemiology of the comorbidity of epilepsy in the general population. Epilepsia 45 2004; 1613-1622
  • 25 Seshadri V, Thomas J, Murthy JMK, Raju CR. Prevalence of depression and its effect on quality of life in PWE: a community based study and a comprehensive rural epilepsy study in South India (CRESSI). Neurol Asia 9 2004; 139 [Abstract]
  • 26 Kanner AM. Recognition of the various expressions of anxiety, psychosis, and aggression in epilepsy. Epilepsia 45 2004; 22-27
  • 27 Ettinger A, Reed M, Cramer J. Depression and comorbidity in community based PWE or asthma. Neurology 63 2004; 1008-1014
  • 28 Strine TW, Kobau R, Chapman DP. et al. Psychological distress, comorbidities, and health behaviors among U. S. adults with seizures: results from the 2002 National Health Interview Survey. Epilepsia 46 2005; 1133-1139
  • 29 Thomson AW, Miller JW, Katon W. et al. Socio demographic and clinical factors associated with depression in epilepsy. Epilepsy Behav 14 April 2009; 655-660
  • 30 Amruth G, Praveen-Kumar S, Nataraju B, Kasturi P. Study of psychiatric comorbidities in epilepsy by using the Mini International Neuropsychiatric Interview. Epilepsy Behav 33 2014; 94-100
  • 31 Herodes M, Õun A, Haldre S, Kaasik AE. Epilepsy in Estonia: a quality-of-life study. Epilepsia 42 2001; 1061-1073
  • 32 Guekht AB, Mitrokhina TV, Lebedeva AV. et al. Factors influencing on quality of life in people with epilepsy. Seizure 16 2007; 128-133
  • 33 Kimiskidis VK, Triantafyllou NI, Karaizou E. et al. Depression and anxiety in epilepsy: the association with demographic and seizure related variables. Ann Gen Psychiatr 6 2007; 28
  • 34 Vickrey BG, Hays RD, Graber J, Rausch R, Engel Jr J, Brook RH. A health related quality of life instrument for patients evaluated for epilepsy surgery. Med Care 30 1992; 299-319
  • 35 Harden CL, Maroof DA, Nikolov B. et al. The effect of seizure severity on quality of life in epilepsy. Epilepsy Behav 11 2007; 208-211
  • 36 Jacoby A, Baker GA, Steen N, Potts P, Chadwick DW. The clinical course of epilepsy and its psychosocial correlates: finding from a U.K. community study. Epilepsia 37 1996; 148-161
  • 37 Kanner AM, Balabanov A. Depression and epilepsy. How closely are they related?. Neurology 58 2002; S27
  • 38 Kanner AM. The complex epilepsy patient: intricacies of assessment and treatment. Epilepsia 44 2003; 3-8
  • 39 Djibuti M, Shakarishvilj R. Influence of clinical, demographic and socioeconomic variables on QOL in patients with epilepsy: findings from Georgian Study. J Neurol Neurosurg Psychiatr 74 2003; 570-573
  • 40 Tracy JI, Dechant V, Sperling MR, Cho R, Glosser D. The association of mood with quality of life ratings in epilepsy. Neurology 68 2007; 1101-1107
  • 41 Gilliam F. Optimizing health outcomes in active epilepsy. Neurology 58 2002; S9-S19
  • 42 Zhao Y, Wu H, Li J. et al. Quality of life and related factors in adult patients with epilepsy in China. Epilepsy Behav 22 2011; 376-379
  • 43 Todorova K. Influence of co-morbid depression, sociodemographic and seizure related variables on quality of life of adults with epilepsy. Scr Sci Medica 42 2010; 209-212
  • 44 Fiordelli E, Beghi E, Bogliun G, Crespi V. Epilepsy and psychiatric disturbance: a cross-sectional study. Br J Psychiatry 163 1993; 446-450
  • 45 Nubukpo P, Cement JP, Houinato D. et al. Psychological issues in PWE in Togo and Benin (West Africa) II: quality of life measured using the QOLIE 31 scale. Epilepsy Behav 5 2004; 728-734