RSS-Feed abonnieren
DOI: 10.1016/j.homp.2004.04.002
The effect of fluorine and homeopathic medicines in rats fed cariogenic diet
Publikationsverlauf
Received16. Juli 2003
revised07. Oktober 2003
accepted19. April 2004
Publikationsdatum:
19. Dezember 2017 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00034926/200403/lookinside/thumbnails/10-1016-j-homp-2004-04-002-1.jpg)
Abstract
Although some sectors of dentistry have benefited from technological advances, dental caries is still a major problem. Prevention and treatment of dental caries by fluorine is considered a major advance in public health. Nevertheless fluorosis, caused by ingestion of excessive amounts of fluorine during the period of teeth formation, is of great concern. In accordance with the homeopathic doctrine, minimum doses of fluorine and other substances could prevent and/or treat caries. In this experiment, we compared the preventive action of fluorine and evaluated the effect of homeopathic medicines on the teeth of rats fed a cariogenic diet. None of the groups included in this study developed caries. However, microscopy revealed the presence of precipitate and/or deposit in the groups treated with homeopathic medicines. This phenomenon might be due to deposit in the dental surface or precipitation of bacterial plaque or calcium salts. It was not possible to identify the composition of the deposit/precipitate due for technical reasons. In one of the groups treated with homeopathic medicines fur loss was observed in 40% of animals. These reactions might be caused due to the action of the homeopathic medicines.
-
References
- 1 OMS—Organização Mundial da Saúde. Levantamentos Básicos em Saúde Bucal. 4th edn. Sao Paulo: Livraria Editora Santos, 1999.
- 2 Bowen W. Wither or whither caries research? Caries Res 1999; 33: 1–3.
- 3 Kidd EAM. Caries management. Dent Clin N Am 1999; 43: 743–763.
- 4 Martof A. Dental Care. Pediatr Rev 2001; 22: 13–15.
- 5 Fejerskov O, Manji F. Risk assessment in dental caries. In: Bader JD (ed). Risk Assessment in Dentistry. Chapel Hill: University of North Carolina Dental College, 1990, pp 215–217.
- 6 Casamassimo P. Relationships between oral and systemic health. Pediatr Clin N Am 2000; 47: 1149–57.
- 7 Cury JA. Uso do flúor e controle da cárie como doença. In: Odontologia Restauradora. Fundamentos e Possibilidades. Org. Baratieri, LN. 1st edn. São Paulo: Santos Editora, 2001. 740pp
- 8 Hahnemann S. Organon da arte de curar. 6th edn. Trad. Por Edméa Marturano e Izao C. Soares, R. Preto: Museu Homeop. A. Brickmann, 1995.
- 9 Poitevin B. Le devenir de l’homéopathie. Elements de théorie et de recherche. Paris: Doin, 1987.
- 10 Eyzayaga FX. Tratado de Medicina Homeopática. 3rd edn. Buenos Aires: Mary Cel, 1992.
- 11 Kossak-Romanach A. Homeopatia em 1000 conceitos, 1st edn. São Paulo: ElCid, 1987.
- 12 Pustiglione M. 17 Lições de Homeopatia: estudos avançdo Organon e leitura atualizada dos “textos maiores” de Samuel Hahnemann. São Paulo: Typus, 2000.
- 13 Pustiglione M. O (moderno) organon da arte de curar, São Paulo: Typus, 2001.
- 14 Pustiglione M. Homeopatia & cuidados básicos de saúde São Paulo: Dinamis, 1998.
- 15 Bratthal D. Caries risk assessment. Malmö University, Faculty of Odontology. Department of Cariology 1997/2000. Disponı́vel em: http://www.db.od.mah.se/car/data/riskbasic.html, http://www.db.od.mah.se/car/data/riskbasic.html>. Acesso em: 02 maio 2001.
- 16 Schüssler apud Blotin. Os doze remédios dos tecidos, tradução Rezende Filho, publicado pela Farmácia e Laboratório Homeoterápico, 1946.
- 17 Bildet J, et al. Etude de l’action de différentes dilutions de Phosphorus sur l’hépatite toxique du rat. Ann Homeop Fr 1975; 4: 425–432 et également Homeop Fr 1984; 72: 199–204 (Spécial: la recherche expérimentale).
- 18 Brunini CR, et al. Repertório Homeopático Pediátrico. São Paulo: Robe Editorial, 2003.
- 19 Boericke W. Matéria Medica Homeopática, 9th edn. São Paulo: Robes, 1997.
- 20 Lamothe J. Homeopatia Pediátrica. São Paulo: Editora Andrei, 1999.
- 21 Tyler ML. Retratos de medicamentos homeopáticos, vol 1. São Paulo: Santos, 1992.
- 22 Regolatti B, Mühlemann HR. Effect of urease inhibition on calculus formation and caries development in the rat. Helv Odont Acta 1971; 15: 151–154.
- 23 Baker HJ, Lindsey SR, Weisbroth SH. The Laboratory Rat Research Applications, vol 2. New York: Academic Press (EUA), 1980.
- 24 Vono BG. Efeito do Ítrio e do Flúor na prevenção da cárie dentária em ratos. Tese apresentada para obtenção do Tı́tulo de livre docência, junto à Faculdade de Odontologia de Bauru—USP, 1977.
- 25 Pekkala E, Hietala EL, Puukka M, Larmas M. The effect of sucrose diet of rat dams on the dentine apposition and dental caries of their pups. Arch Oral Biol 2000; 45: 193–200.
- 26 Oliveira SS. Influência de diversos açúcares na incidência de cárie de molares de ratos. Tese apresentada à Universidade de Odontologia de Bauru para obtenção do grau de Doutor. Bauru 1989, s.n; 93p BR28.1.
- 27 Autio J, Hietala EL, Larmas M. The effect of two sucrose diets on formation of dentin and predentin in growing rats. Acta Odontol Scand 1997; 55: 292–295.
- 28 Huumonen S, Tjaderhane L, Larmas M. Greater concentration of dietary sucrose decreases dentin formation and increases the area of dentinal caries in growing rats. J Nutr 1997; 127: 2226–2230.
- 29 Pekkala E, Hietala EL, Puuka M, Larmas M. Effects of a high sucrose diet and intragastric sucrose feeding on the dentinogenesis, dental caries and mineral excretion of the young rat. Acta Odontol Scand 2000; 58: 155–159.
- 30 Sintes JL, Miller SA. Growth, development and dental caries in rats fed two experimental diets. Arch latinoamericanos nutricion 1983; XXXIII.
- 31 Kortelainen S, Larmas M. Effect of fluoride on the rate dentin apposition and caries progression in young and old Wistar rats. Scand J Dent Res 1994; 102: 30–33.
- 32 Koo H, Rosalen PL, Cury JA, et al. Effect of Apis Mellifera propolis from two Brazilians regions on carie development in desalivated rats. Caries Res 1999; 33: 393–400.
- 33 Kortelainen S, Larmas M. Effect of fluoride on caries progression and dentin apposition in rats fed on a cariogenic or non-cariogenic diet. Scand J Dent Res 1993; 101: 16–20.
- 34 Ruenis AP, Rosalen PL, Velpato MC, Groppo FC. Effects of caffeine and theophylline on the development of dental caries in rats. Biol Pharm Bull 2000; 23: 339–343.
- 35 Lathoud JA. Estudos de matéria médica homeopàtica. São Paulo: Organon, 2001.
- 36 Ribeiro Filho A. Repertório de sintomas—chave em Pediatria Homeopática. Sao Paulo: Organon, 2000.