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Indian Journal of Neurotrauma 2005; 02(02): 107-109
DOI: 10.1016/S0973-0508(05)80024-3
Original Article
Thieme Medical and Scientific Publishers Private Ltd.

Prognostic significance of serum free radical level in head injury

A. Mishra
,
M.F. Huda
,
V.P. Singh
,
S. Mohanty
,
A. Sodhi
*   Department of Biotechnology Banaras Hindu University
› Author Affiliations
Subject Editor:
Further Information

Publication History

Publication Date:
05 April 2017 (online)

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Abstract

There is evidence that free radicals are released following head injury. Serial estimation of free radical levels in serum of isolated head injury cases showed high levels on the day of injury. Cases having parenchyma damage i.e. diffuse axonal injury and brain edema showed significantly high levels until seventh day of injury whereas cases in whom surface hematoma i.e. extradural hematoma was evacuated showed decline of free radical level to normal. Free radical level is reflected in serum possibly due to breakdown brain blood barrier.

Keywords

blood-brain barrier - brain edema - free radicals - head injury prognosis - intracranial hematoma
 

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