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Ackermann, L. : 2022 Science of Synthesis, 2021/5: Electrochemistry in Organic Synthesis DOI: 10.1055/sos-SD-236-00280
Electrochemistry in Organic Synthesis

14 Electrochemistry in Natural Product Synthesis

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Editor: Ackermann, L. 

Authors: Ackermann, L. ; Brown, R. C. D. ; Enders, P.; Fang, P.; Folgueiras-Amador, A. A. ; Francke, R. ; Galczynski, J.; Gosmini, C. ; Hodgson, J. W.; Hou, Z.-W.; Huang, H.; Huang, Z.; Inagi, S. ; Kuciński, K. ; Kuriyama, M. ; Lam, K. ; Lambert, T. H.; Leech, M. C. ; Lennox, A. J. J. ; Lin, Z.; Little, R. D.; Massignan, L.; Mei, T.-S.; Meyer, T. H.; Moeller, K. D. ; Onomura, O. ; Prudlik, A.; Ruan, Z. ; Scheremetjew, A. ; Schiltz, P.; Selt, M.; Villani, E. ; Waldvogel, S. R. ; Wang, Z.-H.; Wu, T.; Xing, Y.-K.; Xu, H.-C. ; Yamamoto, K. 

Title: Electrochemistry in Organic Synthesis

Print ISBN: 9783132442122; Online ISBN: 9783132442146; Book DOI: 10.1055/b000000126

1st edition © 2022. Thieme. All rights reserved.
Georg Thieme Verlag KG, Stuttgart

Subjects: Organic Chemistry;Chemical Reactions, Catalysis;Organometallic Chemistry;Laboratory Techniques, Stoichiometry

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Parent publication

Title: Science of Synthesis

DOI: 10.1055/b-00000101

Series Editors: Fürstner, A. (Editor-in-Chief); Carreira, E. M.; Faul, M.; Kobayashi, S.; Koch, G.; Molander, G. A.; Nevado, C.; Trost, B. M.; You, S.-L.

Type: Multivolume Edition

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Abstract

The multistep synthesis of natural products has historically served as a useful and informative platform for showcasing the best, state-of-the-art synthetic methodologies and technologies. Over the last several decades, electrochemistry has proved itself to be a useful tool for conducting redox reactions. This is primarily due to its unique ability to selectively apply any oxidizing or reducing potential to a sufficiently conductive reaction solution. Electrochemical redox reactions are readily scaled and can be more sustainable than competing strategies based on conventional redox reagents. In this chapter, we summarize the examples where electrochemistry has been used in the synthesis of natural products. The chapter is organized by the reaction type of the electrochemical step and covers both oxidative and reductive reaction modes.

Key words

organic electrochemistry - electrosynthesis - natural products - oxidation - reduction - total synthesis - redox - cyclization
 
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