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Molander, G. A.: 2020 Science of Synthesis, 2019/5: Dual Catalysis in Organic Synthesis 2 DOI: 10.1055/sos-SD-232-00169
Dual Catalysis in Organic Synthesis 2

2.6 Dual Catalysis with Two or More Biocatalysts

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Editor: Molander, G. A.

Authors: Bäckvall, J.-E.; Cruz, F. A.; Deng, Y.-H.; Diéguez, M.; Dong, V. M.; Galman, J. L.; Gröger, H. ; Montgomery, S. L.; Pàmies, O.; Parmeggiani, F.; Shao, Z.; Shi, X.; Turner, N. J.; Vitale, M. R. ; Wang, H.-Y.; Wang, J.; Yamashita, Y.; Zeitler, K. ; Zhao, G.

Title: Dual Catalysis in Organic Synthesis 2

Print ISBN: 978313242981-9; Online ISBN: 978313242985-7; Book DOI: 10.1055/b-006-166041

2020 © 2020 Georg Thieme Verlag KG
Georg Thieme Verlag KG, Stuttgart

Subjects: Organic Chemistry;Chemical Reactions, Catalysis;Organometallic Chemistry;Laboratory Techniques, Stoichiometry

Science of Synthesis Reference Libraries



Parent publication

Title: Science of Synthesis

DOI: 10.1055/b-00000101

Series Editors: Fürstner, A. (Editor-in-Chief); Carreira, E. M.; Faul, M.; Kobayashi, S.; Koch, G.; Molander, G. A.; Nevado, C.; Trost, B. M.; You, S.-L.

Type: Multivolume Edition

Also available at
 

Abstract

The remarkable activity, selectivity, and stability of many commercially available or easily prepared biocatalysts, along with their simple operative conditions and the intrinsic “greenness” of biocatalytic processes, have all contributed to a rapidly accelerating expansion of the research area dedicated to the design and development of one-pot multistep synthetic approaches involving two or more enzymes and/or microbial cells. A brief survey of the literature is presented, focusing mainly on efficient protocols that are generally applicable to a broad range of substrates and relevant to the synthesis of small, often chiral, organic molecules as synthons for the pharmaceutical and fine-chemical industries.

Key words

dual catalysis - biocatalysis - enzymes - microorganisms - green chemistry - cascades - multistep processes - asymmetric synthesis - resolution - deracemization - functional-group interconversion
 
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