10 Intermolecular Transition-Metal-Catalyzed C—C Coupling Reactions in Continuous Flow

Abstract

This chapter provides an up-to-date collection of prominent examples of intermolecular transition-metal-catalyzed C–C coupling reactions performed in continuous-flow systems. The advantages offered by flow technology for the implementation of traditional cross-coupling methods are discussed. Moreover, recent examples of the successful application of flow reactors for C–H functionalization strategies (including C–H activation and dual photoredox transition-metal catalysis) are reviewed.

Schlüsselwörter

transition-metal catalysis - cross coupling - Suzuki–Miyaura coupling - Negishi coupling - Mizoroki–Heck coupling - carbonylative coupling - continuous flow - C–H functionalization - dehydrogenative coupling - C–H activation - dual catalysis

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