10 Intermolecular Transition-Metal-Catalyzed C—C Coupling Reactions in Continuous Flow
Book
Editors: Jamison, T. F.; Koch, G.
Title: Flow Chemistry in Organic Synthesis
Print ISBN: 9783132423312; Online ISBN: 9783132423350; Book DOI: 10.1055/b-006-161272
1st edition © 2018. Thieme. All rights reserved.
Georg Thieme Verlag KG, Stuttgart
Subjects: Organic Chemistry;Chemical Reactions, Catalysis;Organometallic Chemistry;Laboratory Techniques, Stoichiometry
Science of Synthesis Reference Libraries
Parent publication
Title: Science of Synthesis
DOI: 10.1055/b-00000101
Series Editors: Fürstner, A. (Editor-in-Chief); Carreira, E. M.; Faul, M.; Kobayashi, S.; Koch, G.; Molander, G. A.; Nevado, C.; Trost, B. M.; You, S.-L.
Type: Multivolume Edition
Abstract
![](https://www.thieme-connect.de/media/10.1055-b-006-161272/thumbnails/a_216fcj.jpg)
This chapter provides an up-to-date collection of prominent examples of intermolecular transition-metal-catalyzed C–C coupling reactions performed in continuous-flow systems. The advantages offered by flow technology for the implementation of traditional cross-coupling methods are discussed. Moreover, recent examples of the successful application of flow reactors for C–H functionalization strategies (including C–H activation and dual photoredox transition-metal catalysis) are reviewed.
Key words
transition-metal catalysis - cross coupling - Suzuki–Miyaura coupling - Negishi coupling - Mizoroki–Heck coupling - carbonylative coupling - continuous flow - C–H functionalization - dehydrogenative coupling - C–H activation - dual catalysis- 2 Metal-Catalyzed Cross-Coupling Reactions. de Meijere A, Diederich F. Wiley-VCH; Weinheim, Germany 2004
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