1.2 C—C Bond Formation by Hetarene C—H Activation
Buch
Herausgeber: Yu, J.-Q.
Titel: Catalytic Transformations via C—H Activation 1
Untertitel: C-C, C-N, C-O, C-Hal, and C-B Bond Formation
Print ISBN: 9783131711311; Online ISBN: 9783132403413; Buch-DOI: 10.1055/b-003-129295
1st edition © 2016 Thieme. All rights reserved.
Georg Thieme Verlag KG, Stuttgart
Fachgebiete: Organische Chemie;Chemische Reaktionen, Katalyse;Organometallchemie;Chemische Labormethoden, Stöchiometrie
Science of Synthesis Reference Libraries
Übergeordnete Publikation
Titel: Science of Synthesis
DOI: 10.1055/b-00000101
Typ: Mehrbändiges Werk
Abstract
Heteroaromatic compounds play key roles in pharmaceuticals, agrochemicals, and materials, and the development of efficient synthetic methods to access differently substituted hetarenes is therefore an important issue in organic synthesis. To circumvent the limitations associated with classical protocols to form hetaryl—carbon bonds, metal-catalyzed hetarene C—H activation followed by C—C bond-forming reactions has been developed extensively in recent decades. These transformations allow the construction of C—C bonds between hetaryl moieties and all the three differently hybridized carbons to result in alkylation, alkenylation, acylation, alkynylation, etc. of a diverse range of hetarenes irrespective of their electronic characters. This chapter deals with C—C bond formation by hetarene C—H activation achieved by transition-metal catalysis.
Schlüsselwörter
hetarenes - alkylation - alkenylation - arylation - acylation - alkynylation - cyanation-
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