2.6 Metal-Mediated Multicomponent Reactions
Book
Editor: Müller, T. J. J.
Title: Multicomponent Reactions, Volume 2
Subtitle: Reactions Involving an α,α-Unsaturated Carbonyl Compound as Electrophilic Component, Cycloadditions, and Boron-, Silicon-, Free-Radical-, and Metal-Mediated Reactions
Print ISBN: 9783131728319; Online ISBN: 9783132064317; Book DOI: 10.1055/b-003-125831
1st edition © 2014. Thieme. All rights reserved.
Georg Thieme Verlag KG, Stuttgart
Subjects: Multicomponent Reactions
Science of Synthesis Reference Libraries
Parent publication
Title: Science of Synthesis
DOI: 10.1055/b-00000101
Series Editors: Carreira, E. M.; Decicco, C. P.; Fürstner, A.; Molander, G.; Schaumann, E.; Shibasaki, M.; Thomas, E. J.; Trost, B. M.
Type: Multivolume Edition
Abstract
Multicomponent reactions (MCRs) make possible the rapid synthesis of molecular libraries that have a high degree of structural diversity. Metal-mediated multicomponent reactions are particularly interesting as they give access to processes that occur with high chemo-, regio-, and stereoselectivity with excellent functional group tolerance. For example, reductive coupling of two unsaturated compounds on reduced zirconocene affords a variety of zirconacycles, which react with electrophiles to form various carbo- and heterocycles.
Key words
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