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Clarke, P. A. et al.: 2021 Science of Synthesis, 2021/3: Knowledge Updates 2021/3 DOI: 10.1055/sos-SD-110-02000
Knowledge Updates 2021/3

10.24.3 Product Subclass 3: Pyrimido[1,6-a]indoles and Related Benzo-Fused Ring Systems

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Book

Editors: Clarke, P. A.; Joule, J. A.; Marsden, S. P.; Petersson, E. J.

Authors: Grygorenko, O. O. ; Harris, P. A. ; Hollmann, F.; Malins, L. R.; Payne, R. J.; Vashchenko, B. V. 

Title: Knowledge Updates 2021/3

Print ISBN: 9783132442092; Online ISBN: 9783132442115; Book DOI: 10.1055/b000000500

1st edition © 2021 Thieme. All rights reserved.
Georg Thieme Verlag KG, Stuttgart

Subjects: Organic Chemistry;Chemical Reactions, Catalysis;Organometallic Chemistry;Laboratory Techniques, Stoichiometry

Science of Synthesis Knowledge Updates



Parent publication

Title: Science of Synthesis

DOI: 10.1055/b-00000101

Series Editors: Fürstner, A. (Editor-in-Chief); Carreira, E. M.; Faul, M.; Kobayashi, S.; Koch, G.; Molander, G. A.; Nevado, C.; Trost, B. M.; You, S.-L.

Type: Multivolume Edition

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Abstract

Methods for the synthesis of pyrimido[1,6-a]indoles, indolo[1,2-c]quinazolines, and the less-common pyrido[2′,1′:2,3]pyrimido[1,6-a]indol-5-ium ring systems are reviewed in this chapter. Indolo[1,2-c]quinazolines are the most represented in the literature, most often being accessed via cyclization of either 2-(2-aminoaryl)indoles or 2-(2-haloaryl)indoles, although a variety of additional approaches are described.

Key words

pyrimido[1,6-a]indoles - indolo[1,2-c]quinazolines - pyrido[2′,1′:2,3]pyrimido[1,6-a]indol-5-ium salts - cyclization
 
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