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DOI: 10.5999/aps.2015.42.4.478
Potential Use of Transferred Lymph Nodes as Metastasis Detectors after Tumor Excision
Authors
Due to the fact that it reliably results in positive outcomes, lymph node flap transfer is becoming an increasingly popular surgical procedure for the prevention and treatment of lymphedema. This technique has been shown to stimulate lymphoangiogenesis and restore lymphatic function, as well as decreasing infection rates, minimizing pain, and preventing the recurrence of lymphedema. In this article, we investigate possible additional benefits of lymph node flap transfer, primarily the possibility that sentinel lymph nodes may be used to detect micro-metastasis or in-transit metastasis and may function as an additional lymphatic station after the excision of advanced skin cancer.
Publication History
Received: 04 January 2015
Accepted: 07 April 2015
Article published online:
05 May 2022
© 2015. The Korean Society of Plastic and Reconstructive Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonCommercial License, permitting unrestricted noncommercial use, distribution, and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes. (https://creativecommons.org/licenses/by-nc/4.0/)
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REFERENCES
- 1 Becker C, Assouad J, Riquet M. et al. Postmastectomy lymphedema: long-term results following microsurgical lymph node transplantation. Ann Surg 2006; 243: 313-315
- 2 Sapountzis S, Nicoli F, Chilgar R. et al. Evidence-based analysis of lymph node transfer in postmastectomy upper extremity lymphedema. Arch Plast Surg 2013; 40: 450-451
- 3 Gharb BB, Rampazzo A, Spanio di Spilimbergo S. et al. Vascularized lymph node transfer based on the hilar perforators improves the outcome in upper limb lymphedema. Ann Plast Surg 2011; 67: 589-593
- 4 Saaristo AM, Niemi TS, Viitanen TP. et al. Microvascular breast reconstruction and lymph node transfer for postmastectomy lymphedema patients. Ann Surg 2012; 255: 468-473
- 5 Lin CH, Ali R, Chen SC. et al. Vascularized groin lymph node transfer using the wrist as a recipient site for management of postmastectomy upper extremity lymphedema. Plast Reconstr Surg 2009; 123: 1265-1275
- 6 Viitanen TP, Visuri MT, Hartiala P. et al. Lymphatic vessel function and lymphatic growth factor secretion after microvascular lymph node transfer in lymphedema patients. Plast Reconstr Surg Glob Open 2013; 1: 1-9
- 7 Yamamoto T, Yamamoto N, Yamashita M. et al. Efferent lymphatic vessel anastomosis: supermicrosurgical efferent lymphatic vessel-to-venous anastomosis for the prophylactic treatment of subclinical lymphedema. Ann Plast Surg. 11.11.2014
- 8 Soran A, Finegold DN, Brufsky A. Lymphedema prevention and early intervention: a worthy goal. Oncology (Williston Park) 2012; 26 (249) 254-256
- 9 Aladowicz E, Ferro L, Vitali GC. et al. Molecular networks in melanoma invasion and metastasis. Future Oncol 2013; 9: 713-726
- 10 Shesol BF, Nakashima R, Alavi A. et al. Successful lymph node transplantation in rats, with restoration of lymphatic function. Plast Reconstr Surg 1979; 63: 817-823
- 11 Clodius L, Smith PJ, Bruna J. et al. The lymphatics of the groin flap. Ann Plast Surg 1982; 9: 447-458
- 12 Morton DL, Thompson JF, Cochran AJ. et al. Final trial report of sentinel-node biopsy versus nodal observation in melanoma. N Engl J Med 2014; 370: 599-609
- 13 Zbytek B, Carlson JA, Granese J. et al. Current concepts of metastasis in melanoma. Expert Rev Dermatol 2008; 3: 569-585