A clinical efficacy of 30% ethenolic extract of Indian propolis and Recaldent ^TM in management of dentinal hypersensitivity: A comparative randomized clinical trial

ABSTRACT

Objective: The aim of this study is to evaluate the efficacy of 30% ethenolic extract of Indian propolis compared with Recaldent ^TM (casein phosphopeptide-amorphous calcium phosphate) in reduction of dentinals hypersensitivity, a randomized, double-blind, split mouth, controlled clinical trial was conducted among the patients residing in Central Jail. Materials and Methods: A sample of 73 teeth from 13 patients having at least three teeth with dentinal hypersensitivity (DH) were randomly allocated into three treatment groups: Group A: 30% ethenolic extract of Indian propolis, Group B: Recaldent ^TM , Group C: Sterile water. Verbal rating scale was used to record the degree of hypersensitivity based on patient′s response to tactile and air blast stimuli. The baseline scores were obtained. Each intervention group received applications of their respective agents consecutively on 1 ^st , 7 ^th , 14 ^th , and 21 ^st day. After each application the scores were recorded. Results: Both the 30% Indian propolis and Recaldent ^TM showed significant reduction in DH. Conclusions: Recaldent ^TM was found to be significantly better in reducing the DH compared to propolis and sterile water (P < 0.01).

Key words:

Dentin hypersensitivity - Indian propolis - recaldent - split mouth - verbal rating scale

• REFERENCES

• 1 Addy M. Dentine hypersensitivity: New perspectives on an old problem. Int Dent J 2002; 52: 367-75
• 2 Hastings C. Dentinal hypersensitivity-dental hygiene and periodontal considerations. Int Dent J 2002; 52: 385-93
• 3 Porto IC, Andrade AK, Montes MA. Diagnosis and treatment of dentinal hypersensitivity. J Oral Sci 2009; 51: 323-32
• 4 MacCarthy D. Dentine hypersensitivity: A review of the literature. J Ir Dent Assoc 2004; 50: 36-41
• 5 Zandim DL, Corrêa FO, Rossa Júnior C, Sampaio JE. In vitro evaluation of the effect of natural orange juices on dentin morphology. Braz Oral Res 2008; 22: 176-83
• 6 Pashley DH. Dentine permeability and its role in the pathobiology of dentine sensitivity. Arch Oral Biol 1994; 39: 73-80
• 7 Brännström M, Lindén LA, Aström A. The hydrodynamics of the dental tubule and of pulp fluid. A discussion of its significance in relation to dentinal sensitivity. Caries Res 1967; 1: 310-7
• 8 Dowell P, Addy M, Dummer P. Dentine hypersensitivity: Aetiology, differential diagnosis and management. Br Dent J 1985; 158: 92-6
• 9 Cunha-Cruz J, Wataha JC, Zhou L, Manning W, Trantow M, Bettendorf MM. et al. Treating dentin hypersensitivity: Therapeutic choices made by dentists of the northwest precedent network. J Am Dent Assoc 2010; 141: 1097-105
• 10 Herod EL. Cyanoacrylates in dentistry: A review of the literature. J Can Dent Assoc 1990; 56: 331-4
• 11 Geiger S, Matalon S, Blasbalg J, Tung M, Eichmiller FC. The clinical effect of amorphous calcium phosphate (ACP) on root surface hypersensitivity. Oper Dent 2003; 28: 496-500
• 12 GC Tooth Mousse. Available from: http://www.gceurope.com/products/detail.php?id=112 [Cited on 2012 Jun 28]
• 13 Rosaiah K, Aruna K. Clinical efficacy of amorphous calcium phosphate, G. C. Tooth mousse and Glauma desensitizer in treating dentin hypersensitivity. Int J Dent Clinics 2011; 3: 1-4
• 14 Park YK, Koo MH, Ikegaki M, Cury JA, Rosalen PL. Effects of propolis on Streptococcus mutans, Actinomycesnaeslundii, Staphylococcus aureus . Rev Microbiol 1998; 29: 143-8
• 15 Almas K, Dahlan A, Mahmoud A. Propolis as a natural remedy: An update. Saudi Dent J 2001; 13: 45-9
• 16 Ikeno K, Ikeno T, Miyazawa C. Effects of propolis on dental caries in rats. Caries Res 1991; 25: 347-51
• 17 Koo H, Rosalen PL, Cury JA, Park YK, Ikegaki M, Sattler A. Effect of Apis mellifera propolis from two Brazilian regions on caries development in desalivated rats. Caries Res 1999; 33: 393-400
• 18 Bretz WA, Chiego Jr DJ, Marcucci MC, Cunha I, Custódio A, Schneider LG. Preliminary report on the effects of propolis on wound healing in the dental pulp. Z Naturforsch C 1998; 53: 1045-8
• 19 Sales-Peres H, Carvalho FN, Marsicano JA, Mattos MC, Pereira JC, Forim MR. et al. Effect of propolis gel on the in vitro reduction of dentin permeability. J Appl Oral Sci 2011; 19: 318-23
• 20 Mahmoud AS, Almas K, Dahlan AA. The effect of propolis on dentinal hypersensitivity and level of satisfaction among patients from a university hospital Riyadh, Saudi Arabia. Indian J Dent Res 1999; 10: 130-7
• 21 Soben P. Essentials of Preventive and Community Dentistry. 3 rd ed. Arya (MEDI) publishing house, New Delhi: Tooth wear Index; 2006: 202-3
• 22 Assis JS, Rodrigues LK, Fonteles CS, Colares RC, Souza AM, Santiago SL. Dentin hypersensitivity after treatment with desensitizing agents: A randomized, double-blind, split-mouth clinical trial. Braz Dent J 2011; 22: 157-61
• 23 Liu HC, Lan WH, Hsieh CC. Prevalence and distribution of cervical dentin hypersensitivity in a population in Taipei, Taiwan. J Endod 1998; 24: 45-7
• 24 Pérez Mde L, Mayelin Guerra R, Fernández M, Márquez D, Velazco G, Rodríguez J. et al. Effectiveness and safety of tisuacryl in treating dentin hypersensitivity (DH). Medicc Rev 2010; 12: 24-8
• 25 Pérez Ruíz AO. Dolor bucodental. In: Bello Álvarez D, editor El Estomatólogo, Surelación Con El Dolor Y La Sangre. 5 th ed. Havana: Editorial Ciencias Médicas; 2008: 192-209
• 26 Kielbassa AM. Hipersensibilidaddentinaria: Pasos simples para el diagnóstico y tratamientodiario. Int Dent J 2002; 52: 394-6
• 27 Cummins D. Dentin hypersensitivity: From diagnosis to a breakthrough therapy for everyday sensitivity relief. J Clin Dent 2009; 20: 1-9
• 28 Ide M, Wilson RF, Ashley FP. The reproducibility of methods of assessment for cervical dentine hypersensitivity. J Clin Periodontol 2001; 28: 16-22
• 29 Sowinski J, Ayad F, Petrone M, DeVizio W, Volpe A, Ellwood R. et al. Comparative investigations of the desensitising efficacy of a new dentifrice. J Clin Periodontol 2001; 28: 1032-6
• 30 Kleinberg I. Dentinal hypersensitivity, Part II: Treatment of sensitive dentin. Compend Contin Educ Dent 1986; 7:280: 282-4
• 31 Shen P, Cai F, Nowicki A, Vincent J, Reynolds EC. Remineralization of enamel subsurface lesions by sugar-free chewing gum containing casein phosphopeptide-amorphous calcium phosphate. J Dent Res 2001; 80: 2066-70
• 32 Reynolds EC, Cain CJ, Webber FL, Black CL, Riley PF, Johnson IH. et al. Anticariogenicity of calcium phosphate complexes of tryptic casein phosphopeptides in the rat. J Dent Res 1995; 74: 1272-9
• 33 Kowalczyk A, Botuliñski B, Jaworska M, Kierklo A, Pawiñska M, Dabrowska E. Evaluation of the product based on Recaldent technology in the treatment of dentin hypersensitivity. Adv Med Sci 2006; 51: 40-2
• 34 Holland GR, Narhi MN, Addy M, Gangarosa L, Orchardson R. Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. J Clin Periodontol 1997; 24: 808-13
• 35 Vieira AH, Santiago SL. Management of dentinal hypersensitivity. Gen Dent 2009; 57: 120-6
• 36 Sharma N, Roy S, Kakar A, Greenspan DC, Scott R. A clinical study comparing oral formulations containing 7.5% calcium sodium phosphosilicate (NovaMin), 5% potassium nitrate, and 0.4% stannous fluoride for the management of dentin hypersensitivity. J Clin Dent 2010; 21: 88-92
• 37 Salian S, Thakur S, Kulkarni S, LaTorre G. A randomized controlled clinical study evaluating the efficacy of two desensitizing dentifrices. J Clin Dent 2010; 21: 82-7
• 38 Tirapelli C, Panzeri H, Soares RG, Peitl O, Zanotto ED. A novel bioactive glass-ceramic for treating dentin hypersensitivity. Braz Oral Res 2010; 24: 381-7
• 39 Gillam DG, Newman HN. Assessment of pain in cervical dentinal sensitivity studies. A review. J Clin Periodontol 1993; 20: 383-94
• 40 Lussi A, Schaffner M. Progression of and risk factors for dental erosion and wedge-shaped defects over a 6-year period. Caries Res 2000; 34: 182-7