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Planta Med 1989; 55(5): 463-466
DOI: 10.1055/s-2006-962065
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© Georg Thieme Verlag Stuttgart · New York

Indole Alkaloids from Alstonia angustifolia

Wen-lan Hu, Ji-ping Zhu, Manfred Hesse
  • Organisch-chemisches Institut der Universität Zürich, Winterthurerstraße 190, CH-8057 Zürich, Switzerland
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Publication History

1988

Publication Date:
24 January 2007 (online)

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Abstract

From the stem bark of Alstonia angustifolia, eleven alkaloids were isolated. Seven of them are known ones: echitamine (1), N(b)-demethylechitamine (2), pseudoakuammigine (3), tubotaiwine (5), akuammicine (6), N(b)-β-methylantirhine (12), and N(b)-methylakuammidine (13). The four others, pseudoakuammigine N-oxide (4), akuammicine N-oxide (7), N(b)-demethylalstogustine (8), and N(b)-demethylalstogustine N-oxide (11), are new alkaloids. Their structures were determined by means of spectroscopic analysis and chemical correlation with known alkaloids.