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Synthesis 2005(1): 25-27  
DOI: 10.1055/s-2004-834935
SHORTPAPER
© Georg Thieme Verlag Stuttgart · New York

An Expeditious Synthesis of 2,4-Disubstituted 2-Imidazolin-5-ones

Said Oumouch, Maryline Bourotte, Martine Schmitt*, Jean-Jacques Bourguignon
Laboratoire de Pharmacochimie de la Communication Cellulaire, UMR 7081 CNRS/ULP, Université Louis Pasteur, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch-Graffenstaden, France
Fax: +33(3)90244310; e-Mail: schmitt@pharma.u-strasbg.fr;
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Received 19 July 2004
Publikationsdatum:
03. Dezember 2004 (online)

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Abstract

2-Thiomethylimidazolin-5-one undergoes efficient palladium-catalyzed cross-coupling with boronic acids and organostannanes mediated by copper(I) thiophene-2-carboxylate.

Key words

imidazolones - palladium - boronic acids - organostannanes - copper(I) thiophene carboxylate