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Synthesis 2003(9): 1383-1386
DOI: 10.1055/s-2003-40211
DOI: 10.1055/s-2003-40211
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York
One-Pot Synthesis of 3,4-Dihydro-2(1H)-Quinazolinones through Palladium-Catalyzed Intramolecular Arylation of Ureas
Weitere Informationen
Publikationsverlauf
Received
27 February 2003
Publikationsdatum:
24. Juni 2003 (online)


Abstract
3,4-Dihydro-2(1H)-quinazolinone derivatives 3-3b have been synthesized through a one-pot palladium-catalyzed heterocyclization from N-benzyl-N-(2-bromoarylmethyl)amines 1-1b and aliphatic or aromatic isocyanates 2.
Key words
quinazolinone - palladium - arylations - isocyanates - urea - cyclizations