Synlett 2002(10): 1700-1702
DOI: 10.1055/s-2002-34244
LETTER
© Georg Thieme Verlag Stuttgart · New York

Asymmetric Michael Reactions Using Tartrate-based Magnesium Catalysts

Alasdair C. MacCullocha, Sylvie Yolkab, Richard F. W. Jackson* a,b
a Department of Chemistry, Bedson Building, The University of Newcastle upon Tyne, Newcastle upon Tyne, NE1 7RU, UK
b Department of Chemistry, Dainton Building, The University of Sheffield, Sheffield, S3 7HF, UK
e-Mail: r.f.w.jackson@shef.ac.uk;
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Publikationsverlauf

Received 8 August 2002
Publikationsdatum:
23. September 2002 (online)

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Abstract

Catalysts derived from a combination of dialkyl tartrates and dibutylmagnesium are effective for the asymmetric Michael addition of dibenzyl malonate to enones with ee’s up to 58%.