Synlett 2002(2): 0263-0266
DOI: 10.1055/s-2002-19747
LETTER
© Georg Thieme Verlag Stuttgart · New York

Asymmetric Reduction of Cyclic Enones to Allylic Alcohols

Jérôme Hannedouchea, Jennifer A. Kennya, Tim Walsgroveb, Martin Wills*a
a Department of Chemistry, University of Warwick, Coventry, CV4 7AL, UK
Fax: +24(7652)4112; e-Mail: m.wills@warwick.ac.uk;
b Glaxo SmithKline Pharmaceuticals, Old Powder Mills, Nr Leigh, Tonbridge, Kent, TN11 9AN, UK
Further Information

Publication History

Received 11 December 2001
Publication Date:
02 February 2007 (online)

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Abstract

Asymmetric transfer hydrogenation of cyclic enones results in highly enantioselective reduction to cyclic allylic alcohols.