Thromb Haemost 1992; 68(03): 257-260
DOI: 10.1055/s-0038-1656360
Original Article
Schattauer GmbH Stuttgart

Detection of Asymptomatic Deep Vein Thrombosis by Real-Time B-Mode Ultrasonography in Hip Surgery Patients

Giancarlo Agnelli
1   The Istituto di Medicina Interna e di Medicina Vascolare, Università di Perugia, Perugia, Italy
,
Raul Volpato
1   The Istituto di Medicina Interna e di Medicina Vascolare, Università di Perugia, Perugia, Italy
,
Stefano Radicchia
1   The Istituto di Medicina Interna e di Medicina Vascolare, Università di Perugia, Perugia, Italy
,
Franca Veschi
1   The Istituto di Medicina Interna e di Medicina Vascolare, Università di Perugia, Perugia, Italy
,
Paolo Di Filippo
2   The Istituto di Clinica Ortopedica e, Università di Perugia, Perugia, Italy
,
Luciano Lupattelli
3   The Istituto di Radiologia, Università di Perugia, Perugia, Italy
,
Giuseppe G Nenci
1   The Istituto di Medicina Interna e di Medicina Vascolare, Università di Perugia, Perugia, Italy
› Author Affiliations
Further Information

Publication History

Received 31 January 1992

Accepted after revision 16 April 1992

Publication Date:
04 July 2018 (online)

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Summary

The aim of this study was to prospectively evaluate the accuracy of real-time B-mode ultrasonography in the diagnosis of asymptomatic proximal deep vein thrombosis (DVT) in hip surgery patients. Venography was adopted as the gold standard. We studied 100 consecutive patients undergoing hip surgery: 60 patients for hip fracture and 40 patients for elective hip replacement. Bilateral real-time B-mode ultrasonography was performed prior to bilateral venography. The two diagnostic procedures were performed on the same day by different investigators unaware of the assigned prophylatic regimen for DVT Compressibility of the vein segment was adopted as the single criterion for DVT. Venography was performed and judged by radiologists unaware of the ultrasonography results. In 13 limbs venography was either impossible to perform or not adequate for judgement. Ultrasonography and an adequate venography was obtained in 187 limbs. A venography proven DVT was observed in 49 limbs (26.2%) and a proximal DVT in 21 limbs (11.2%). All the patients were asymptomatic for DVT. The sensitivity and specificity of real time B-mode ultrasonography for proximal DVT were 57% (95% confidence interval: C. I. 36–80) and 99% (C. I. 99–100), respectively and the positive and negative predictive values were 93% (C.I. 73–100) and 95% (C.I. 91–97), respectively. The sensitivity and specificity for overall DVT were 25% (C.I. 11–38) and 99% (C.I. 97–100), respectively and the positive and negative predictive values were 92% (C. I. 73–100) and 79% (C.I. 76–85), respectively. Our data indicate that realtime B-mode ultrasonography for its high specificity could make venography unnecessary in patients with positive results. However, because of its low sensitivity it cannot be used for the screening of DVT in asymptomatic patients, nor can it replace venography for outcome measurements in clinical trials on DVT prophylaxis.