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Synthesis 2017; 49(21): 4759-4768
DOI: 10.1055/s-0036-1588431
DOI: 10.1055/s-0036-1588431
special topic
Radical Metal-Free Borylation of Aryl Iodides
Authors
Further Information
Publication History
Received: 21 March 2017
Accepted after revision: 02 May 2017
Publication Date:
29 May 2017 (online)
Published as part of the Special Topic Modern Strategies for Borylation in Synthesis
Abstract
A simple metal-free borylation of aryl iodides mediated by a fluoride sp2–sp3 diboron adduct is described. The reaction conditions are compatible with various functional groups. Electronic effects of substituents do not affect the borylation while steric hindrance does. The reaction proceeds via a radical mechanism in which pyridine serves to stabilize the boryl radicals, generated in situ.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1588431.
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