Planta Med 2011; 77(6): 672-678
DOI: 10.1055/s-0030-1250549
Tropical Diseases
Reviews
© Georg Thieme Verlag KG Stuttgart · New York

Curcuma as a Parasiticidal Agent: A Review

Mohamed Haddad1 , 2 , Michel Sauvain1 , 2 , Eric Deharo1 , 2
  • 1Laboratoire de pharmacochimie des substances naturelles et pharmacophores redox, UMR 152, UPS, Université de Toulouse, Toulouse, France
  • 2IRD, UMR-152, Mission IRD, Casilla 18-1209 Lima, Peru
Further Information

Publication History

received May 21, 2010 revised October 20, 2010

accepted October 23, 2010

Publication Date:
23 November 2010 (online)

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Abstract

Members of the Curcuma plant species (Zingiberaceae) have been used for centuries in cooking, cosmetics, staining and in traditional medicine as “omnipotent” remedies. Herbal preparations made with, and molecules extracted from, Curcuma have been shown to possess a wide variety of pharmacological properties against malignant proliferation, hormonal disorders, inflammation, and parasitosis among other conditions. This review evaluates Curcuma and its associated bioactive compounds, particularly focusing on studies examining the parasiticidal activity of these components against the tropical parasites Plasmodium, Leishmania, Trypanosoma, Schistosoma and more generally against other cosmopolitan parasites (nematodes, Babesia, Candida, Giardia, Coccidia and Sarcoptes).